Interactor 1: PSA6 (P60900)
Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)
Gene: PSMA6

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~Proteasome, AAA_lid_3~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 246
Hs

1 406
+ At
+ Sp
+ At
+ At
+ Hs
+ Hs
+ Rn
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024