Protein: IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha)

Gene: IDH3A
Organism: Drosophila melanogaster
Interactions: 186
UniProt ID: Q9VWH4

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004449 - isocitrate dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006099 - tricarboxylic acid cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1321646

Q8MT18
Isocitrate dehydrogenase

2

15

High-throughput

0.737

High

1471298

Q9VD58
Isocitric dehydrogenase subunit beta

1

15

High-throughput

0.575

High

55486

A1Z9E3
Elongation factor Tu

2

2

High-throughput

0.571

High

1268204

Q7KN94
Electron transfer flavoprotein subunit alpha

2

1

High-throughput

0.571

High

1378507

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

2

High-throughput

0.571

High

1473331

ATD3A
ATPase family AAA domain-containing protein 3A homolog

2

8

High-throughput

0.571

High

1485451

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

2

High-throughput

0.571

High

1487138

Q9VV75
AT02348p

2

3

High-throughput

0.571

High

875496

KARG
Arginine kinase 1

2

0

High-throughput

0.547

High

1479438

NFS1
Cysteine desulfurase, mitochondrial

2

0

High-throughput

0.547

High

198107

PRS8
26S proteasome regulatory subunit 8

2

4

High-throughput

0.521

High

264541

O62602
mitogen-activated protein kinase kinase

2

2

High-throughput

0.521

High

438018

PYR1
Multifunctional protein r

2

3

High-throughput

0.521

High

704411

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

3

High-throughput

0.521

High

715173

CLH
Clathrin heavy chain

2

1

High-throughput

0.521

High

782818

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

1

High-throughput

0.521

High

875310

TCPG
T-complex protein 1 subunit gamma

2

1

High-throughput

0.521

High

1012004

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

2

1

High-throughput

0.521

High

1265761

Q7K3H0
LD28067p

2

1

High-throughput

0.521

High

1265872

Q7K3J0
T-complex protein 1 subunit theta

2

1

High-throughput

0.521

High

1267753

Q7KMQ0
26S proteasome regulatory subunit 7

2

4

High-throughput

0.521

High

1465486

Q9V455
Importin subunit alpha

2

1

High-throughput

0.521

High

1468097

Q9VAL7
Calnexin 99A, isoform A

2

1

High-throughput

0.521

High

1468500

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

1

High-throughput

0.521

High

1475006

IPO9
Importin-9

2

4

High-throughput

0.521

High

1479205

Q9VK57
PIH1 domain-containing protein 1

2

1

High-throughput

0.521

High

1484326

Q9VQL1
serine--tRNA ligase

2

2

High-throughput

0.521

High

1485408

Q9VS57
RE14391p

2

1

High-throughput

0.521

High

1487836

RS10B
Small ribosomal subunit protein eS10B

2

3

High-throughput

0.521

High

1487886

Q9Y162
vesicle-fusing ATPase

2

6

High-throughput

0.521

High

661881

FUSED
Serine/threonine-protein kinase fused

1

1

High-throughput

0.494

High

627031

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

1069221

Q0E8E8
Phosphate carrier protein, mitochondrial

1

7

High-throughput

0.479

High

1070842

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

2

High-throughput

0.479

High

1197347

Q500Y7
GEO11443p1

1

2

High-throughput

0.479

High

1268232

Q7KN97
Pyruvate carboxylase

1

5

High-throughput

0.479

High

1377518

Q95RF6
LD34461p

1

2

High-throughput

0.479

High

1465647

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

2

High-throughput

0.479

High

1478915

Q9VK06
Phospholipid-transporting ATPase

1

0

High-throughput

0.458

High

1484951

Q9VRL0
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

567606

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

2

High-throughput

0.445

High

1070129

Q0E9E2
Pyruvate carboxylase

1

2

High-throughput

0.445

High

1234135

SARM1
NAD(+) hydrolase sarm1

1

1

High-throughput

0.445

High

1261592

Q7JR58
Probable enoyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.445

High

1262020

Q7JUS9
Phosphate carrier protein, mitochondrial

1

7

High-throughput

0.445

High

1268742

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

1

High-throughput

0.445

High

1346077

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

1

High-throughput

0.445

High

1376876

LDH
L-lactate dehydrogenase

1

5

High-throughput

0.445

High

1487879

Q9W1H8
acetyl-CoA C-acyltransferase

1

2

High-throughput

0.445

High

356916

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

1

High-throughput

0.442

High

1472112

INO80
Chromatin-remodeling ATPase INO80

1

2

High-throughput

0.442

High

52716

A1Z729
NADP-retinol dehydrogenase

1

3

High-throughput

0.437

High

94139

D5AEK7
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform E

1

2

High-throughput

0.437

High

561610

SPTCA
Spectrin alpha chain

1

2

High-throughput

0.437

High

612420

ACTN
Alpha-actinin, sarcomeric

1

1

High-throughput

0.437

High

654407

DDX6
ATP-dependent RNA helicase me31b

1

5

High-throughput

0.437

High

1172911

RS5A
Small ribosomal subunit protein uS7A

1

2

High-throughput

0.437

High

1263401

Q7JYX2
NADP-retinol dehydrogenase

1

3

High-throughput

0.437

High

1267998

TERA
Transitional endoplasmic reticulum ATPase TER94

1

4

High-throughput

0.437

High

1269272

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.437

High

1463788

RAB5
Ras-related protein Rab5

1

1

High-throughput

0.437

High

1468689

Q9VAY2
Heat shock protein 83

1

7

High-throughput

0.437

High

1473217

Q9VEV3
Tetratricopeptide repeat protein 1

1

3

High-throughput

0.437

High

1475546

Q9VH62
LD44003p

1

3

High-throughput

0.437

High

1482354

Q9VN44
FI07923p

1

3

High-throughput

0.437

High

1484623

Q9VR42
Serine/threonine-protein kinase RIO3

1

3

High-throughput

0.437

High

144901

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.426

High

909886

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.426

High

55835

A1Z9K0
Uncharacterized protein, isoform B

1

1

High-throughput

0.407

High

58118

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.407

High

263421

PENG
Protein penguin

1

2

High-throughput

0.407

High

304165

RAB7
Ras-related protein Rab7

1

4

High-throughput

0.407

High

355999

O96692
small monomeric GTPase

1

1

High-throughput

0.407

High

620825

TNNT
Troponin T, skeletal muscle

1

2

High-throughput

0.407

High

669740

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.407

High

726500

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.407

High

875042

PRS4
26S proteasome regulatory subunit 4

1

6

High-throughput

0.407

High

911498

IMA
Importin subunit alpha

1

1

High-throughput

0.407

High

911794

POLO
Serine/threonine-protein kinase polo

1

1

High-throughput

0.407

High

1057364

ARL2
ADP-ribosylation factor-like protein 2

1

2

High-throughput

0.407

High

1069783

Q0E931
GTP-binding protein 1

1

5

High-throughput

0.407

High

1173972

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

1

High-throughput

0.407

High

1176030

MCM4
DNA replication licensing factor MCM4

1

1

High-throughput

0.407

High

1176375

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

7

High-throughput

0.407

High

1263259

Q7JXU4
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.407

High

1267859

Q7KN04
Spondin-1

1

1

High-throughput

0.407

High

1344163

Q8SY39
ATP-dependent RNA helicase DDX54

1

3

High-throughput

0.407

High

1378847

Q960C7
NADP-retinol dehydrogenase

1

3

High-throughput

0.407

High

1457465

XPO1
Exportin-1

1

2

High-throughput

0.407

High

1464479

Q9V3V6
26S proteasome regulatory complex subunit p50

1

9

High-throughput

0.407

High

1464892

Q9V405
26S proteasome regulatory subunit 6B

1

4

High-throughput

0.407

High

1465213

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.407

High

1466782

Q9V9Q4
LD43819p

1

1

High-throughput

0.407

High

1467978

Q9VAH7
N-terminal kinase-like protein

1

1

High-throughput

0.407

High

1471262

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

4

High-throughput

0.407

High

1471693

Q9VDK7
Signal recognition particle subunit SRP72

1

1

High-throughput

0.407

High

1472788

Q9VEH0
Aluminum tubes, isoform A

1

1

High-throughput

0.407

High

1475515

CARM1
Probable histone-arginine methyltransferase CARMER

1

2

High-throughput

0.407

High

1476818

ARL8
ADP-ribosylation factor-like protein 8

1

1

High-throughput

0.407

High

1477474

DDX47
ATP-dependent RNA helicase DDX47

1

4

High-throughput

0.407

High

1479172

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

1

High-throughput

0.407

High

1480053

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

3

High-throughput

0.407

High

1484360

Q9VQL7
Fatty acid synthase

1

2

High-throughput

0.407

High

1487092

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

2

High-throughput

0.407

High

1487630

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.407

High

1487871

Q9VXR5
ATP-binding cassette sub-family F member 2

1

1

High-throughput

0.407

High

1487872

RENT1
Regulator of nonsense transcripts 1 homolog

1

1

High-throughput

0.407

High

1487873

Q9VZ88
AT07585p

1

1

High-throughput

0.407

High

1487876

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.407

High

1487880

Q9W392
T-complex protein 1 subunit beta

1

3

High-throughput

0.407

High

1487882

Q9W414
Regulatory particle triple-A ATPase 4

1

4

High-throughput

0.407

High

1487883

Q9W4N8
LD30122p

1

2

High-throughput

0.407

High

1487885

SYQ
Probable glutamine--tRNA ligase

1

2

High-throughput

0.407

High

51932

PO210
Nuclear pore membrane glycoprotein 210

2

0

High-throughput

0.298

High

53725

A1Z843
Nodal modulator 3

2

0

High-throughput

0.298

High

482807

TPM2
Tropomyosin-2

2

0

High-throughput

0.298

High

652123

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

0

High-throughput

0.298

High

753221

GLT
Glutactin

2

0

High-throughput

0.298

High

852243

COPB
Coatomer subunit beta

2

0

High-throughput

0.298

High

1264572

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.298

High

1267422

Q7KLX3
Translocon-associated protein subunit delta

2

0

High-throughput

0.298

High

1343183

Q8STG9
DSec61alpha

2

0

High-throughput

0.298

High

1346290

Q8T8W3
AT21416p

2

0

High-throughput

0.298

High

1346450

MESD
LDLR chaperone boca

2

0

High-throughput

0.298

High

1377727

FAXC
Failed axon connections

2

0

High-throughput

0.298

High

1465402

KRH2
Krueppel homolog 2

2

0

High-throughput

0.298

High

1469689

Q9VBU5
3-dehydrosphinganine reductase

2

0

High-throughput

0.298

High

1476314

Q9VHL2
T-complex protein 1 subunit eta

2

0

High-throughput

0.298

High

1487870

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

0

High-throughput

0.298

High

1487874

Q9VZL3
very-long-chain enoyl-CoA reductase

2

0

High-throughput

0.298

High

652982

VND
Homeobox protein vnd

1

0

High-throughput

0.265

Low

1481700

Q9VMD4
FI03607p

1

0

High-throughput

0.265

Low

1486220

Q9VTT3
LD31163p

1

0

High-throughput

0.265

Low

69001

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.249

Low

771378

MYSP2
Paramyosin, short form

1

0

High-throughput

0.249

Low

1173605

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.249

Low

1260780

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

1306496

Q8IRH7
Supercoiling factor variant B

1

0

High-throughput

0.249

Low

1374622

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.249

Low

1463214

FADD
Fas-associated death domain protein

1

0

High-throughput

0.249

Low

1469956

ATLAS
Atlastin

1

0

Small-scale

0.249

Low

1470363

Q9VCF8
LD23561p

1

0

High-throughput

0.249

Low

1475977

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.249

Low

1479266

Q9VK69
T-complex protein 1 subunit delta

1

0

High-throughput

0.249

Low

1484426

Q9VQS4
Spindly

1

0

High-throughput

0.249

Low

53189

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

197113

O18332
FI01544p

1

0

High-throughput

0.232

Low

304283

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

360600

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

633051

GLNA2
Glutamine synthetase 2 cytoplasmic

1

0

High-throughput

0.232

Low

823807

SQH
Myosin regulatory light chain sqh

1

0

High-throughput

0.232

Low

829692

ARF4
ADP ribosylation factor 4

1

0

High-throughput

0.232

Low

834883

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

852989

ACTZ
Actin-related protein 1

1

0

High-throughput

0.232

Low

1059190

ROP
Protein ROP

1

0

High-throughput

0.232

Low

1236940

MOX12
MOXD1 homolog 2

1

0

High-throughput

0.232

Low

1237057

Q6NP72
GEO09659p1

1

0

High-throughput

0.232

Low

1265013

ARC1
Activity-regulated cytoskeleton associated protein 1

1

0

High-throughput

0.232

Low

1268050

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

0

High-throughput

0.232

Low

1268373

DYM
Dymeclin

1

0

High-throughput

0.232

Low

1321308

Q8MSI2
GH15296p

1

0

High-throughput

0.232

Low

1321469

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1344257

Q8SY53
GH11935p

1

0

High-throughput

0.232

Low

1378657

Q95WY3
Nucleolar protein 56

1

0

High-throughput

0.232

Low

1409514

Q9BN17
Echinoid

1

0

High-throughput

0.232

Low

1465151

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

1473050

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.232

Low

1477170

Q9VI53
LD44267p

1

0

High-throughput

0.232

Low

1477855

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.232

Low

1483016

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.232

Low

1483675

Q9VPX5
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.232

Low

1484219

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

1485777

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

1486021

Q9VT75
N-terminal amino-acid N(alpha)-acetyltransferase NatA

1

0

High-throughput

0.232

Low

1486317

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

1486660

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1486919

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.232

Low

1487692

Q9VW70
FI21813p1

1

0

High-throughput

0.232

Low

1487867

Q9VWL0
Mec2

1

0

High-throughput

0.232

Low

1487868

SUN
Protein stunted

1

0

High-throughput

0.232

Low

1487869

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1487875

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

1487877

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

1487878

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.232

Low

1487881

Q9W3N1
RH59310p

1

0

High-throughput

0.232

Low

1487884

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025