HitPredict

Interactor 1: PSA6 (P60900)
Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain)
Gene: PSMA6

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	30659753, 16503656
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 81
+	Hs
		893645 PSA6_HUMAN (1-246): 2.11e-110: 319: 100.00		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		893646 PSA6_HUMAN (1-246): 2.11e-110: 319: 100.00		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		474930 PSA2_HUMAN (7-243): 8.3e-104: 302: 35.44		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		637693 PSA2_HUMAN (7-243): 8.3e-104: 302: 35.44		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		637385 PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		638108 PSA4_HUMAN (6-239): 5.7e-93: 275: 32.35		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Hs
		656197 PSA5_HUMAN (1-242): 4.79e-96: 282: 25.91		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		637386 PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91		RL40_HUMAN (1-76): 3.79e-33: 112: 57.90
+	Hs
		156296 PSA7_HUMAN (9-240): 1.34e-97: 286: 33.62		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		656238 PSA5_HUMAN (1-242): 4.79e-96: 282: 25.91		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		474931 PSA4_HUMAN (6-239): 5.7e-93: 275: 32.35		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		637431 PSA1_HUMAN (1-245): 2.4e-94: 279: 25.91		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		638136 PSA4_HUMAN (6-239): 5.7e-93: 275: 32.35		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Sc
		408276 PSA2_YEAST (13-242): 1.35e-36: 131: 33.47		RS31_YEAST (1-70): 3.03e-30: 105: 52.86