Protein: DUS3
Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase VHR) (Vaccinia H1-related phosphatase) (VHR)

Gene: DUS3, DUSP3
Organism: Homo sapiens
Interactions: 77
UniProt ID: P51452

Gene Ontology (top 5):
GO:0001772 - immunological synapse
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

691683

MK03
Mitogen-activated protein kinase 3

2

20

Small-scale

0.799

High

703504

MK01
Mitogen-activated protein kinase 1

2

20

Small-scale

0.799

High

168655

CSKP
Peripheral plasma membrane protein CASK

1

5

High-throughput

0.698

High

321206

ERLN2
Erlin-2

2

4

High-throughput

0.628

High

326684

DUS14
Dual specificity protein phosphatase 14

1

20

High-throughput

0.618

High

703918

DUS1
Dual specificity protein phosphatase 1

1

15

High-throughput

0.618

High

902916

DUS3
Dual specificity protein phosphatase 3

1

17

High-throughput

0.618

High

902920

DUSP2
Dual specificity protein phosphatase 2

1

18

High-throughput

0.618

High

902931

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.618

High

902958

DS13B
Dual specificity protein phosphatase 13B

1

17

High-throughput

0.618

High

902959

DUS12
Dual specificity protein phosphatase 12

1

19

High-throughput

0.618

High

893676

MEOX1
Homeobox protein MOX-1

2

2

High-throughput

0.606

High

902937

DAAF8
Dynein axonemal assembly factor 8

2

0

High-throughput

0.602

High

283219

ERLN1
Erlin-1

2

3

High-throughput

0.574

High

902924

NDF1
Neurogenic differentiation factor 1

1

2

High-throughput

0.541

High

902918

ARF5
ADP-ribosylation factor 5

1

9

High-throughput

0.536

High

902919

PO3F1
POU domain, class 3, transcription factor 1

1

3

High-throughput

0.536

High

902925

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

15

High-throughput

0.536

High

902936

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

902944

KIF2C
Kinesin-like protein KIF2C

1

5

High-throughput

0.536

High

902949

GSX1
GS homeobox 1

1

3

High-throughput

0.536

High

239357

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

High-throughput

0.518

High

451604

GPX1
Glutathione peroxidase 1

1

0

High-throughput

0.513

High

611805

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

708938

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.513

High

902917

BI1
Bax inhibitor 1

1

0

High-throughput

0.513

High

902940

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

902942

DACT3
Dapper homolog 3

1

0

High-throughput

0.513

High

902955

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.513

High

362991

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.501

High

421747

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

902932

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

1

3

High-throughput

0.489

High

902941

CRGN
Gamma-crystallin N

1

1

High-throughput

0.489

High

902946

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

3

High-throughput

0.489

High

902947

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

1

High-throughput

0.489

High

902950

IFT22
Intraflagellar transport protein 22 homolog

1

10

High-throughput

0.489

High

241131

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

659409

CRCM
Colorectal mutant cancer protein

1

3

High-throughput

0.479

High

841661

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

11

High-throughput

0.479

High

881131

FAS
Fatty acid synthase

1

2

High-throughput

0.479

High

892249

5NTC
Cytosolic purine 5'-nucleotidase

1

1

High-throughput

0.479

High

902921

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

10

High-throughput

0.479

High

902922

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

5

High-throughput

0.479

High

902929

DOC11
Dedicator of cytokinesis protein 11

1

2

High-throughput

0.479

High

902934

TAXB1
Tax1-binding protein 1

1

11

High-throughput

0.479

High

902935

HOOK3
Protein Hook homolog 3

1

11

High-throughput

0.479

High

902948

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

902956

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

902957

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

902962

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.479

High

882598

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.470

High

767732

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

880444

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.458

High

902952

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

High-throughput

0.458

High

330084

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.445

High

902928

H90B4
Putative heat shock protein HSP 90-beta 4

1

1

High-throughput

0.445

High

902953

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

902960

GAB2
GRB2-associated-binding protein 2

1

2

High-throughput

0.445

High

105599

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

902954

CLC1B
C-type lectin domain family 1 member B

1

1

High-throughput

0.437

High

598708

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

902923

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

902938

TTC9C
Tetratricopeptide repeat protein 9C

1

5

High-throughput

0.407

High

902939

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

2

0

High-throughput

0.318

High

387810

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.279

Low

626427

CXCL2
C-X-C motif chemokine 2

1

0

High-throughput

0.279

Low

773830

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

902926

CART

1

0

High-throughput

0.279

Low

902930

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

902933

CF120
UPF0669 protein C6orf120

1

0

High-throughput

0.279

Low

902943

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.279

Low

902945

CCD32
Coiled-coil domain-containing protein 32

1

0

High-throughput

0.279

Low

902961

NTNG1
Netrin-G1

1

0

High-throughput

0.279

Low

379952

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

902927

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.249

Low

902951

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025