HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ITPR2 (Q14571)
Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)
Gene: ITPR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 2701
+	Hs
		900470 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ITPR2_HUMAN (1-2701): 0: 4407: 100.00
+	Hs
		894014 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		950999 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		900474 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		545379 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		436303 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		892374 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		ITPR1_HUMAN (1-2695): 0: 3987: 68.01
+	Hs
		894011 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Hs
		950998 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Hs
		900471 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ITPR3_HUMAN (4-2687): 0: 3912: 64.48
+	Hs
		545378 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ITPR3_HUMAN (4-2687): 0: 3912: 64.48