Protein: HXC4
Homeobox protein Hox-C4 (Homeobox protein CP19) (Homeobox protein Hox-3E)

Gene: HXC4, HOXC4
Organism: Homo sapiens
Interactions: 55
UniProt ID: P09017

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

478307

HXB5
Homeobox protein Hox-B5

3

19

High-throughput

0.861

High

478311

PO2F1
POU domain, class 2, transcription factor 1

1

20

Small-scale

0.724

High

177164

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

3

20

High-throughput

0.667

High

274080

ANR17
Ankyrin repeat domain-containing protein 17

3

20

High-throughput

0.667

High

222003

NCK2
Cytoplasmic protein NCK2

3

13

High-throughput

0.654

High

478308

XRCC6
X-ray repair cross-complementing protein 6

2

6

Small-scale

0.636

High

478315

HD
Huntingtin

2

1

High-throughput

0.628

High

405705

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.618

High

478330

ANKH1
Ankyrin repeat and KH domain-containing protein 1

3

20

High-throughput

0.609

High

478338

ERBIN
Erbin

3

6

High-throughput

0.609

High

478346

RBGP1
Rab GTPase-activating protein 1

3

6

High-throughput

0.609

High

478317

CLK3
Dual specificity protein kinase CLK3

2

4

High-throughput

0.606

High

478321

CSK21
Casein kinase II subunit alpha

2

6

High-throughput

0.606

High

478342

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

1

High-throughput

0.606

High

85232

RBG10
Rab GTPase-activating protein 1-like, isoform 10

3

3

High-throughput

0.599

High

478343

EXOS5
Exosome complex component RRP46

2

0

High-throughput

0.580

High

216367

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

3

High-throughput

0.573

High

478340

NSD3
Histone-lysine N-methyltransferase NSD3

1

6

High-throughput

0.573

High

478310

RINI
Ribonuclease inhibitor

1

6

High-throughput

0.536

High

478312

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

478319

ATX1
Ataxin-1

1

3

High-throughput

0.515

High

478322

SETB1
Histone-lysine N-methyltransferase SETDB1

1

8

High-throughput

0.515

High

478328

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

10

High-throughput

0.515

High

478332

PIAS4
E3 SUMO-protein ligase PIAS4

1

4

High-throughput

0.515

High

478333

LMO3
LIM domain only protein 3

1

15

High-throughput

0.515

High

478335

KAT5
Histone acetyltransferase KAT5

1

3

High-throughput

0.515

High

162441

ANM5
Protein arginine N-methyltransferase 5

1

3

High-throughput

0.508

High

478336

ANM6
Protein arginine N-methyltransferase 6

1

3

High-throughput

0.508

High

421351

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

361071

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

478324

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

478344

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

3

High-throughput

0.489

High

478337

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

9

Small-scale

0.481

High

478309

XRCC5
X-ray repair cross-complementing protein 5

1

6

Small-scale

0.479

High

109358

G5E9A7
DM1 locus, WD repeat containing

1

5

High-throughput

0.470

High

245851

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.470

High

369591

A2MG
Alpha-2-macroglobulin

1

4

High-throughput

0.470

High

478313

GRN
Progranulin

1

1

High-throughput

0.470

High

478320

1433G
14-3-3 protein gamma

1

1

High-throughput

0.470

High

478329

Q86WV8
TSC complex subunit 1

1

2

High-throughput

0.470

High

478334

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

2

High-throughput

0.470

High

478323

TSN
Translin

1

0

High-throughput

0.460

High

463287

LYN
Tyrosine-protein kinase Lyn

1

7

Small-scale

0.437

High

478316

NRAM1
Natural resistance-associated macrophage protein 1

1

0

High-throughput

0.426

High

96871

E9PDP5
Ankyrin repeat and KH domain containing 1

1

20

High-throughput

0.407

High

478325

RBG1L
Rab GTPase-activating protein 1-like

1

4

High-throughput

0.407

High

478331

ELMD2
ELMO domain-containing protein 2

1

0

High-throughput

0.282

High

478341

RNF32
RING finger protein 32

1

0

High-throughput

0.282

High

451681

PGK2
Phosphoglycerate kinase 2

1

0

High-throughput

0.279

Low

478339

CHM4A
Charged multivesicular body protein 4a

1

0

High-throughput

0.279

Low

478314

SYUA
Alpha-synuclein

1

0

High-throughput

0.268

Low

478318

DYN2
Dynamin-2

1

0

High-throughput

0.268

Low

478326

Q5SUL5
HLA class I histocompatibility antigen A alpha chain

1

0

High-throughput

0.268

Low

478345

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

478327

S46A3
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025