HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: RASA3 (Q14644)
Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein)
Gene: RASA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RasGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 834
+	Hs
		1056349 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RASA3_HUMAN (1-834): 0: 887: 100.00
+	Hs
		925282 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RASA3_HUMAN (1-834): 0: 887: 100.00
+	Hs
		564448 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18
+	Mm
		925821 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		IQGA1_MOUSE (114-807): 1.18e-105: 359: 14.29
+	Hs
		809436 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18
+	Hs
		809255 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18
+	Hs
		564517 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		IQGA2_HUMAN (56-817): 1.1e-81: 289: 13.62
+	Hs
		1040058 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		IQGA2_HUMAN (56-817): 1.1e-81: 289: 13.62
+	Hs
		925259 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		IQGA2_HUMAN (56-817): 1.1e-81: 289: 13.62
+	Hs
		564412 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		NF1_HUMAN (298-654): 7.91e-72: 260: 23.15
+	Hs
		598525 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		NF1_HUMAN (298-654): 7.91e-72: 260: 23.15
+	Hs
		598457 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		NF1_HUMAN (298-654): 7.91e-72: 260: 23.15
+	Hs
		564593 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		IQGA3_HUMAN (157-569): 2.92e-65: 240: 14.75
+	Hs
		1201453 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		IQGA3_HUMAN (157-569): 2.92e-65: 240: 14.75
+	Hs
		925404 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		IQGA3_HUMAN (157-569): 2.92e-65: 240: 14.75
+	Hs
		1139212 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DAB2P_HUMAN (4-145): 5.09e-17: 88.4: 17.81
+	Hs
		925347 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DAB2P_HUMAN (4-145): 5.09e-17: 88.4: 17.81
+	Hs
		564728 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		NGAP_HUMAN (8-145): 1.36e-11: 70.7: 15.49
+	Hs
		1330979 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		NGAP_HUMAN (8-145): 1.36e-11: 70.7: 15.49
+	Hs
		925530 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SYGP1_HUMAN (4-118): 9.95e-11: 68: 22.95