Protein: FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (Inactive PPIase FKBP6) (36 kDa FK506-binding protein) (36 kDa FKBP) (FKBP-36) (FK506-binding protein 6) (FKBP-6) (Immunophilin FKBP36)

Gene: FKBP6
Organism: Homo sapiens
Interactions: 98
UniProt ID: O75344

Gene Ontology (top 5):
GO:0000795 - synaptonemal complex
GO:0001650 - fibrillar center
GO:0005528 - FK506 binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276684

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

3

7

High-throughput

0.861

High

276650

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

3

16

Small-scale

0.843

High

276720

EFC4B
EF-hand calcium-binding domain-containing protein 4B

2

2

High-throughput

0.783

High

276712

CK5P3
CDK5 regulatory subunit-associated protein 3

5

1

High-throughput

0.726

High

276693

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.712

High

107788

SUMO5
Small ubiquitin-related modifier 5

2

4

High-throughput

0.706

High

276669

OSBP1
Oxysterol-binding protein 1

4

4

High-throughput

0.702

High

276654

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

4

8

High-throughput

0.699

High

276662

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.691

High

276664

CDK4
Cyclin-dependent kinase 4

1

7

High-throughput

0.691

High

276718

LZTS2
Leucine zipper putative tumor suppressor 2

3

6

High-throughput

0.683

High

276705

IHO1
Interactor of HORMAD1 protein 1

4

0

High-throughput

0.674

High

276732

NDK7
Nucleoside diphosphate kinase homolog 7

3

5

High-throughput

0.667

High

134425

EF2K
Eukaryotic elongation factor 2 kinase

3

1

High-throughput

0.667

High

171133

MYPT1
Protein phosphatase 1 regulatory subunit 12A

3

5

High-throughput

0.667

High

184049

ACOX3
Peroxisomal acyl-coenzyme A oxidase 3

3

1

High-throughput

0.667

High

208606

SI1L1
Signal-induced proliferation-associated 1-like protein 1

3

1

High-throughput

0.667

High

239290

MYPT2
Protein phosphatase 1 regulatory subunit 12B

3

5

High-throughput

0.667

High

276690

GRDN
Girdin

3

5

High-throughput

0.667

High

276698

CD37L
Hsp90 co-chaperone Cdc37-like 1

3

10

High-throughput

0.667

High

276683

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

9

Small-scale

0.647

High

253466

ANM3
Protein arginine N-methyltransferase 3

3

0

High-throughput

0.638

High

276682

RED
Protein Red

3

0

High-throughput

0.638

High

276702

UBE3D
E3 ubiquitin-protein ligase E3D

3

0

High-throughput

0.638

High

276715

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

3

0

High-throughput

0.638

High

276678

MEOX2
Homeobox protein MOX-2

2

5

High-throughput

0.633

High

276672

PDE4A
3',5'-cyclic-AMP phosphodiesterase 4A

2

6

High-throughput

0.628

High

276661

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

276685

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

17

Small-scale

0.618

High

276696

KSR2
Kinase suppressor of Ras 2

1

15

High-throughput

0.618

High

276722

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

3

8

High-throughput

0.609

High

276655

K2C75
Keratin, type II cytoskeletal 75

2

2

High-throughput

0.606

High

276674

EF1D
Elongation factor 1-delta

2

3

High-throughput

0.606

High

276675

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

2

5

High-throughput

0.606

High

276694

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

11

High-throughput

0.606

High

71503

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.580

High

276681

RNF4
E3 ubiquitin-protein ligase RNF4

2

0

High-throughput

0.580

High

276701

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.580

High

276706

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

276710

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

276711

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

276714

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

276723

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.580

High

276727

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

117613

K9JA46
Epididymis luminal secretory protein 52

1

20

High-throughput

0.575

High

276673

PROP
Properdin

2

1

High-throughput

0.561

High

261353

TBL1X
F-box-like/WD repeat-containing protein TBL1X

2

10

High-throughput

0.558

High

192351

GSC2
Homeobox protein goosecoid-2

2

5

High-throughput

0.553

High

276652

PIAS2
E3 SUMO-protein ligase PIAS2

2

1

High-throughput

0.553

High

276688

ECM1
Extracellular matrix protein 1

2

1

High-throughput

0.553

High

276699

RFIP2
Rab11 family-interacting protein 2

2

2

High-throughput

0.553

High

276725

TMM9B
Transmembrane protein 9B

2

1

High-throughput

0.553

High

276668

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.541

High

276658

APOD
Apolipoprotein D

1

2

High-throughput

0.536

High

276659

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

2

High-throughput

0.536

High

276663

PYGM
Glycogen phosphorylase, muscle form

1

2

High-throughput

0.536

High

276665

MYH1
Myosin-1

1

3

High-throughput

0.536

High

276666

MYH7
Myosin-7

1

3

High-throughput

0.536

High

276667

MYH8
Myosin-8

1

3

High-throughput

0.536

High

276671

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.536

High

276677

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

4

High-throughput

0.536

High

276680

ACTS
Actin, alpha skeletal muscle

1

3

High-throughput

0.536

High

276686

TEBP
Prostaglandin E synthase 3

1

11

High-throughput

0.536

High

276687

CDC37
Hsp90 co-chaperone Cdc37

1

10

High-throughput

0.536

High

276692

P5CR3
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.536

High

276708

OSBP2
Oxysterol-binding protein 2

1

4

High-throughput

0.536

High

276733

MYH4
Myosin-4

1

3

High-throughput

0.536

High

276657

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.515

High

276730

CHIP
E3 ubiquitin-protein ligase CHIP

1

16

High-throughput

0.515

High

276660

KCRM
Creatine kinase M-type

1

0

High-throughput

0.513

High

276679

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.513

High

276729

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

276704

ZDH17
Palmitoyltransferase ZDHHC17

1

10

High-throughput

0.504

High

276709

ACD
Adrenocortical dysplasia protein homolog

1

1

High-throughput

0.504

High

276719

TINF2
TERF1-interacting nuclear factor 2

1

2

High-throughput

0.504

High

276670

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.493

High

276676

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.493

High

276726

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

1

High-throughput

0.489

High

276656

F107A
Actin-associated protein FAM107A

1

1

Small-scale

0.481

High

276707

TRI63
E3 ubiquitin-protein ligase TRIM63

1

15

High-throughput

0.481

High

276721

TRI55
Tripartite motif-containing protein 55

1

17

High-throughput

0.481

High

276653

RMP
Unconventional prefoldin RPB5 interactor 1

1

2

High-throughput

0.479

High

276689

FX4L6
Forkhead box protein D4-like 6

1

2

High-throughput

0.479

High

276697

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

3

High-throughput

0.479

High

276700

PIWL4
Piwi-like protein 4

1

14

High-throughput

0.479

High

276716

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

1

High-throughput

0.479

High

97277

E9PSE9
Coiled-coil domain containing 198

1

1

High-throughput

0.470

High

276695

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

276728

FAME
Factor associated with metabolism and energy

1

1

High-throughput

0.439

High

276691

Q4G1B2
Regulator of G-protein signaling 9

1

1

High-throughput

0.437

High

276713

DAA10
Dynein axonemal assembly factor 10

1

1

High-throughput

0.437

High

276703

Q86SX1
Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens

1

20

High-throughput

0.407

High

276717

F118B
Protein FAM118B

3

0

High-throughput

0.347

High

276724

WDCP
WD repeat and coiled-coil-containing protein

3

0

High-throughput

0.347

High

276731

DLGP4
Disks large-associated protein 4

2

0

High-throughput

0.316

High

276651

CCNK
Cyclin-K

1

0

High-throughput

0.282

High

183833

VGF
Neurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025