HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ANKL2 (Q86XL3)
Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4)
Gene: ANKLE2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 938
+	Hs
		951128 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		900653 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		545477 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		436387 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		892466 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		ANKL2_HUMAN (1-938): 0: 1602: 100.00