HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0005737 - cytoplasm GO:0007030 - Golgi organization GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 2054
+	Hs
		564633 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		925488 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		900754 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		545537 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		892521 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		1183487 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		724757 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		724776 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		545482 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		MY18B_HUMAN (1024-1700): 3.43e-34: 146: 11.13
+	Hs
		564757 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84
+	Hs
		725125 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		725138 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		925728 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MYO5B_HUMAN (1603-2051): 4.65e-14: 80.6: 9.19
+	Hs
		1183623 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84