HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: BIN3 (Q9NQY0)
Bridging integrator 3
Gene: BIN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0007015 - actin filament organization GO:0008104 - protein localization GO:0010591 - regulation of lamellipodium assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 253
+	Hs
		131231 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		BIN1_HUMAN (7-223): 7.75e-64: 211: 17.72
+	Hs
		925374 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DNMBP_HUMAN (17-248): 7.08e-62: 211: 18.30
+	Sp
		963941 CDC42_SCHPO (1-191): 2.1e-81: 241: 81.77		HOB3_SCHPO (1-250): 9.59e-71: 219: 27.00
+	Hs
		894149 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DNMBP_HUMAN (17-248): 7.08e-62: 211: 18.30
+	Hs
		951095 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		DNMBP_HUMAN (17-248): 7.08e-62: 211: 18.30
+	Hs
		892443 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		DNMBP_HUMAN (17-248): 7.08e-62: 211: 18.30
+	Hs
		925314 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RHG44_HUMAN (7-229): 9.52e-42: 153: 18.64
+	Hs
		894068 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RHG44_HUMAN (7-229): 9.52e-42: 153: 18.64
+	Hs
		925354 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RHG17_HUMAN (7-228): 2.62e-24: 103: 15.52
+	Hs
		894126 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		RHG17_HUMAN (7-228): 2.62e-24: 103: 15.52
+	Hs
		925755 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		3BP1_HUMAN (22-227): 2.32e-10: 62.1: 12.28