HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: C42S2 (Q9NRR3)
CDC42 small effector protein 2 (Small effector of CDC42 protein 2)
Gene: CDC42SE2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.962

Property	Details
Experiments	28514442, 33961781, 26496610, 10816584, 31980649, 31871319, unassigned2173
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 84
+	Hs
		1330937 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		C42S2_HUMAN (1-84): 1.45e-51: 157: 100.00
+	Hs
		925652 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		C42S2_HUMAN (1-84): 1.45e-51: 157: 100.00
+	Hs
		925653 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		C42S1_HUMAN (1-65): 2.89e-31: 106: 55.88
+	Hs
		894485 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		C42S1_HUMAN (1-65): 2.89e-31: 106: 55.88