HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: C42S1 (Q9NRR8)
CDC42 small effector protein 1 (CDC42-binding protein SCIP1) (Small effector of CDC42 protein 1)
Gene: CDC42SE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	28514442, 33961781, 10816584, 20936779
Identification Methods	affinity chromatography technology, two hybrid, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 79
+	Hs
		925653 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		C42S1_HUMAN (1-79): 2.98e-46: 143: 100.00
+	Hs
		1330937 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		C42S2_HUMAN (1-67): 6.15e-32: 107: 56.72
+	Hs
		925652 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		C42S2_HUMAN (1-67): 6.15e-32: 107: 56.72
+	Hs
		894484 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		C42S2_HUMAN (1-67): 6.15e-32: 107: 56.72