HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SUN2 (Q9UH99)
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2)
Gene: SUN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007097 - nuclear migration GO:0030335 - positive regulation of cell migration
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 717
+	Hs
		1330972 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		925706 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		951436 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		901020 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		545685 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		436559 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		892663 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		299725 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299654 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299649 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299656 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299651 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299627 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299620 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		299648 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		SUN1_HUMAN (1-715): 0: 780: 33.51