Protein: O46067
Hypoxia up-regulated protein 1

Gene: O46067, Grp170
Organism: Drosophila melanogaster
Interactions: 91
UniProt ID: O46067

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

234776

Q9VHA8
LD25575p

2

20

High-throughput

0.737

High

234801

Q9VUC1
Hsc70Cb, isoform A

1

18

High-throughput

0.575

High

234770

Q9VAL7
Calnexin 99A, isoform A

2

6

High-throughput

0.571

High

234804

Q9VW19
Phenoloxidase-activating factor 2

2

8

High-throughput

0.521

High

234792

Q9VPN5
Stress-induced-phosphoprotein 1

1

20

High-throughput

0.514

High

234735

CALR
Calreticulin

1

6

High-throughput

0.479

High

234741

UGGG
UDP-glucose:glycoprotein glucosyltransferase

1

2

High-throughput

0.479

High

234750

SEELE
Protein seele

1

0

High-throughput

0.458

High

234740

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.445

High

234744

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

4

High-throughput

0.445

High

234745

NCPR
NADPH--cytochrome P450 reductase

1

5

High-throughput

0.445

High

234747

Q76NR6
Regucalcin

1

1

High-throughput

0.445

High

234751

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

234754

Q7KN85
ATP-citrate synthase

1

5

High-throughput

0.445

High

234760

Q8T0L3
E1 ubiquitin-activating enzyme

1

4

High-throughput

0.445

High

234761

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.445

High

234772

Q9VEB1
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.445

High

234773

Q9VG31
Malic enzyme

1

3

High-throughput

0.445

High

234774

Q9VGK3
peptidylprolyl isomerase

1

9

High-throughput

0.445

High

234778

Q9VIE8
Aconitate hydratase, mitochondrial

1

5

High-throughput

0.445

High

234781

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

3

High-throughput

0.445

High

234782

Q9VL70
HL08109p

1

1

High-throughput

0.445

High

234787

SYAC
Alanine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

234794

Q9VQ61
Aspartate aminotransferase

1

2

High-throughput

0.445

High

234795

Q9VQL1
serine--tRNA ligase

1

1

High-throughput

0.445

High

234809

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

6

High-throughput

0.445

High

234810

Q9W3X6
fumarate hydratase

1

3

High-throughput

0.445

High

234812

CISY
Probable citrate synthase, mitochondrial

1

3

High-throughput

0.445

High

68863

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

1

High-throughput

0.437

High

85778

B8A405
Ferritin

1

3

High-throughput

0.437

High

234746

Q6NPB4
SD15476p

1

1

High-throughput

0.437

High

234766

Q9V415
HMG-coA reductase degradation 3, isoform A

1

1

High-throughput

0.437

High

234793

Q9VPN8
Peptidase S1 domain-containing protein

1

3

High-throughput

0.437

High

234758

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.426

High

234775

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.426

High

234789

Q9VM43
PDGF- and VEGF-related factor 2

1

0

High-throughput

0.426

High

234813

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

47736

A0AQH0
Proteasome subunit beta

1

9

High-throughput

0.407

High

57495

A1ZB71
Glutathione S transferase E6

1

2

High-throughput

0.407

High

57726

A1ZB77
Uncharacterized protein, isoform J

1

2

High-throughput

0.407

High

234525

VINC
Vinculin

1

4

High-throughput

0.407

High

234731

INO1
Inositol-3-phosphate synthase

1

1

High-throughput

0.407

High

234732

HP1
Heterochromatin protein 1

1

6

High-throughput

0.407

High

234733

ALF
Fructose-bisphosphate aldolase

1

3

High-throughput

0.407

High

234734

PSA1
Proteasome subunit alpha type-1

1

6

High-throughput

0.407

High

234736

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

11

High-throughput

0.407

High

234737

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

1

High-throughput

0.407

High

234742

DALY
Division abnormally delayed protein

1

2

High-throughput

0.407

High

234743

NETB
Netrin-B

1

3

High-throughput

0.407

High

234748

Q7JWV7
Tetraspanin

1

3

High-throughput

0.407

High

234749

Q7JX87
1-Cys peroxiredoxin

1

4

High-throughput

0.407

High

234752

Q7K148
Proteasome subunit beta

1

8

High-throughput

0.407

High

234755

FRIH
Ferritin heavy chain

1

3

High-throughput

0.407

High

234756

Q7KTW5
Inositol-1-monophosphatase

1

1

High-throughput

0.407

High

234757

Q8IQZ7
FI19014p1

1

4

High-throughput

0.407

High

234762

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

3

High-throughput

0.407

High

234763

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

3

High-throughput

0.407

High

234767

PSA3
Proteasome subunit alpha type-3

1

8

High-throughput

0.407

High

234768

TPP2
Tripeptidyl-peptidase 2

1

1

High-throughput

0.407

High

234769

Q9V9U3
LD45254p

1

3

High-throughput

0.407

High

234771

Q9VAN7
Phosphoglycerate mutase

1

2

High-throughput

0.407

High

234777

DPP3
Dipeptidyl peptidase 3

1

1

High-throughput

0.407

High

234779

Q9VKW5
Prolyl endopeptidase

1

3

High-throughput

0.407

High

234780

EF1D
Probable elongation factor 1-delta

1

3

High-throughput

0.407

High

234783

FKB59
FK506-binding protein 59

1

15

High-throughput

0.407

High

234784

Q9VLB7
Rab GDP dissociation inhibitor

1

4

High-throughput

0.407

High

234785

AK200
A-kinase anchor protein 200

1

11

High-throughput

0.407

High

234788

Q9VLS7
LD21067p

1

4

High-throughput

0.407

High

234791

Q9VMZ9
RE36666p

1

1

High-throughput

0.407

High

234796

Q9VQL7
Fatty acid synthase

1

3

High-throughput

0.407

High

234797

Q9VRD6
NTF2-related export protein

1

3

High-throughput

0.407

High

234798

Q9VRL1
GEO06356p1

1

2

High-throughput

0.407

High

234799

Q9VRP2
Uncharacterized protein, isoform A

1

4

High-throughput

0.407

High

234800

Q9VTY2
Uncharacterized protein, isoform A

1

2

High-throughput

0.407

High

234803

Q9VVL7
Dihydrolipoyl dehydrogenase

1

5

High-throughput

0.407

High

234805

Q9VW59
Rho GDP-dissociation inhibitor 3

1

1

High-throughput

0.407

High

234806

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

High-throughput

0.407

High

234808

SND1
Staphylococcal nuclease domain-containing protein 1

1

5

High-throughput

0.407

High

234811

Q9W3Y3
Calcyclin-binding protein

1

8

High-throughput

0.407

High

234814

PSB3
Proteasome subunit beta type-3

1

6

High-throughput

0.407

High

234815

Q9Y112
BcDNA.GH10614

1

2

High-throughput

0.407

High

234786

Q9VLL5
Alpha-N-acetylglucosaminidase

2

0

High-throughput

0.298

High

234738

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.232

Low

234739

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

234753

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

234759

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.232

Low

234764

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.232

Low

234765

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.232

Low

234790

Q9VMY5
beta-mannosidase

1

0

High-throughput

0.232

Low

234802

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.232

Low

234807

Q9VZY0
LD45195p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025