HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: BI2L1 (Q9UHR4)
BAR/IMD domain-containing adapter protein 2-like 1 (Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1) (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate)
Gene: BAIAP2L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0032956 - regulation of actin cytoskeleton organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 511
+	Hs
		564725 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		1330974 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		925709 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		951439 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		564744 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		1330995 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		925741 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		894597 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		564738 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		1330988 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		925732 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		894589 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		951457 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		564730 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		PACN3_HUMAN (7-400): 5.44e-74: 242: 12.71
+	Hs
		1330981 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		PACN3_HUMAN (7-400): 5.44e-74: 242: 12.71
+	Hs
		925717 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		PACN3_HUMAN (7-400): 5.44e-74: 242: 12.71
+	Hs
		894574 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PACN3_HUMAN (7-400): 5.44e-74: 242: 12.71
+	Hs
		925414 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		NOSTN_HUMAN (19-409): 8.83e-43: 160: 15.37
+	Hs
		894191 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		NOSTN_HUMAN (19-409): 8.83e-43: 160: 15.37
+	Hs
		894047 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ITSN1_HUMAN (6-491): 1.88e-27: 119: 11.80