HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1139
+	Hs
		564728 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		1330979 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		1139212 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Hs
		925347 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Hs
		925530 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		564517 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		1040058 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		925259 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		564593 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Hs
		564448 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		1201453 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Hs
		925404 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		IQGA3_HUMAN (127-711): 9.03e-135: 449: 12.44
+	Hs
		809436 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Mm
		925821 RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31		IQGA1_MOUSE (126-751): 1.8e-133: 446: 12.33
+	Hs
		809255 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		1056349 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		RASA3_HUMAN (169-570): 2.21e-123: 401: 25.97
+	Hs
		925282 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		RASA3_HUMAN (169-570): 2.21e-123: 401: 25.97
+	Hs
		564412 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Hs
		598525 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Hs
		598457 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17