HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0010008 - endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 258
+	Hs
		436244 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		895549 RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98		RAB1B_HUMAN (42-256): 2.47e-79: 239: 22.69
+	Mm
		895587 RAB10_MOUSE (3-181): 4.07e-93: 272: 75.98		RAB1B_MOUSE (42-256): 3.61e-79: 239: 22.69
+	Hs
		951020 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		892305 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		895472 RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		918879 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RAB1A_HUMAN (39-256): 5.65e-82: 246: 21.92
+	Zm
		73944 B4FAE1_MAIZE (1-205): 3e-88: 259: 53.17		B4FAE1_MAIZE (42-256): 7.26e-82: 246: 24.54
+	Mm
		1321974 RAB13_MOUSE (1-206): 2.37e-89: 262: 62.62		RAB1B_MOUSE (42-256): 3.61e-79: 239: 22.69
+	Hs
		845881 RAB13_HUMAN (1-206): 3.19e-89: 262: 61.17		RAB1B_HUMAN (42-256): 2.47e-79: 239: 22.69
+	Hs
		1079964 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RAB1B_HUMAN (42-256): 2.47e-79: 239: 22.69
+	Hs
		925305 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		845845 RAB13_HUMAN (1-206): 3.19e-89: 262: 61.17		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Mm
		919000 RAB1A_MOUSE (1-204): 1.23e-87: 258: 54.41		RAB1B_MOUSE (42-256): 3.61e-79: 239: 22.69
+	Hs
		914093 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		900511 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		545307 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		RAC2_HUMAN (50-233): 5.11e-77: 233: 56.52
+	Hs
		894052 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		564470 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		1079966 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26