HitPredict

Interactor 1: UB2D1 (P61080)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: Ube2d1

Interactor 2: LIN41 (Q1PSW8)
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)
Gene: Trim71

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19898466
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Mm			1 855
+	Hs
		1318738 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM2_HUMAN (166-855): 6.27e-156: 476: 27.18
+	Hs
		262201 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM3_HUMAN (169-855): 3.5e-149: 458: 29.53
+	Hs
		262161 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRIM3_HUMAN (169-855): 3.5e-149: 458: 29.53
+	Hs
		584907 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		RO52_HUMAN (171-639): 2.1e-86: 285: 12.66
+	Hs
		1318719 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM5_HUMAN (173-623): 2.37e-78: 264: 13.32
+	Hs
		849316 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI32_HUMAN (168-855): 2.42e-77: 266: 16.67
+	Hs
		1336390 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI39_HUMAN (177-630): 5.81e-77: 261: 12.07
+	Hs
		170304 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TIF1A_HUMAN (70-624): 1.54e-71: 257: 16.17
+	Hs
		849366 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI22_HUMAN (179-624): 4.12e-75: 255: 12.50
+	Hs
		1333889 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI45_HUMAN (78-598): 5.83e-70: 243: 21.85
+	Hs
		1356055 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRIM1_HUMAN (54-506): 2.73e-68: 242: 16.34
+	Hs
		1151762 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		Q6GX22_HUMAN (52-619): 3.43e-68: 241: 15.15
+	Hs
		537142 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI27_HUMAN (171-603): 2.87e-69: 240: 12.84
+	Hs
		536760 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI27_HUMAN (171-603): 2.87e-69: 240: 12.84
+	Hs
		1313765 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI62_HUMAN (179-642): 2.32e-68: 236: 14.38
+	Hs
		849320 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TIF1B_HUMAN (82-475): 1.11e-63: 231: 22.69
+	Hs
		175730 UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84		TRI18_HUMAN (55-500): 1.01e-61: 223: 15.71
+	Hs
		175653 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		TRI18_HUMAN (55-500): 1.01e-61: 223: 15.71
+	Ce
		715104 UBC2_CAEEL (1-147): 7.45e-82: 239: 89.12		NHL1_CAEEL (146-512): 1.35e-30: 131: 12.53
+	Hs
		849346 UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00		NHLC1_HUMAN (567-811): 5.95e-15: 79.9: 17.58