HitPredict

Interactor 1: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28581483
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 156
+	Hs
		895773 UB2D3_HUMAN (30-173): 1.29e-73: 219: 31.51		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		70479 UB2E3_HUMAN (5-173): 2.2e-72: 218: 26.90		B2RDW1_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Hs
		895774 UB2D3_HUMAN (30-173): 1.29e-73: 219: 31.51		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		88580 UB2D1_RAT (30-173): 2.47e-75: 224: 30.14		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Mm
		476737 UB2D3_MOUSE (30-173): 1.29e-73: 219: 31.51		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	At
		1091932 UBC28_ARATH (30-174): 5.45e-76: 225: 31.29		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		475249 UB2D4_HUMAN (30-173): 3.96e-76: 226: 32.19		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		715116 UBC8_ARATH (30-174): 1.21e-75: 225: 32.65		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Dm
		639414 UBCD1_DROME (30-173): 5.31e-75: 223: 32.88		Q9W418_DROME (1-77): 1.7e-34: 127: 100.00
+	At
		715132 UBC9_ARATH (30-174): 3.95e-75: 223: 31.29		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		715147 UBC10_ARATH (30-174): 5.61e-75: 223: 31.97		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		474984 UB2D2_HUMAN (30-173): 3.54e-75: 223: 32.19		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		715157 UBC11_ARATH (30-174): 1.28e-74: 222: 34.01		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		1137415 UB2E3_HUMAN (5-173): 2.2e-72: 218: 26.90		Q5U5U6_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Hs
		475124 UB2E3_HUMAN (5-173): 2.2e-72: 218: 26.90		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		639385 UBC1_ARATH (26-173): 7.67e-70: 210: 28.00		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		790155 UBC2_ARATH (26-173): 5.52e-70: 210: 28.00		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		474958 UBE2A_HUMAN (26-172): 2.67e-69: 208: 28.19		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00