HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: UHRF2 (Q96PU4)
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)
Gene: UHRF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, UQ_con~ubiquitin
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 802
+	Hs
		1299596 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		849415 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		919833 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		895886 UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		72154 B3KSH4_HUMAN (104-200): 1.63e-61: 187: 100.00		UHRF2_HUMAN (1-802): 0: 964: 100.00
+	Hs
		849419 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		919835 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		895889 UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Hs
		896525 UBE2N_HUMAN (27-153): 1.06e-37: 129: 51.97		UHRF1_HUMAN (1-802): 0: 817: 53.01
+	Zm
		13330 A0A1D6FSE0_MAIZE (4-155): 1e-74: 224: 42.11		A0A1D6FSK8_MAIZE (419-766): 1.4e-75: 260: 17.32