HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 232
+	Hs
		1290204 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN125_HUMAN (1-232): 1.03e-55: 179: 100.00
+	Hs
		849314 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI26_HUMAN (22-228): 2.25e-46: 163: 14.88
+	Hs
		1377468 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN114_HUMAN (9-225): 2.79e-44: 150: 29.26
+	Hs
		584907 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RO52_HUMAN (22-227): 1.26e-41: 149: 13.30
+	Hs
		1283434 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN166_HUMAN (1-224): 1.46e-42: 145: 30.83
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (28-229): 3.66e-38: 140: 16.90
+	Hs
		1318532 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI31_HUMAN (22-226): 5.82e-36: 133: 12.50
+	Hs
		1285831 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI43_HUMAN (24-229): 1.32e-35: 132: 15.09
+	Hs
		1318738 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM2_HUMAN (17-227): 1.61e-34: 131: 13.97
+	Hs
		1377469 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI17_HUMAN (22-226): 6.96e-35: 131: 15.32
+	Hs
		1318719 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM5_HUMAN (24-229): 2.94e-33: 126: 15.81
+	Hs
		849318 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRAF3_HUMAN (5-175): 4.42e-33: 127: 19.89
+	Hs
		537142 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI27_HUMAN (22-228): 7.77e-33: 125: 15.49
+	Hs
		1261313 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		RN138_HUMAN (21-222): 4.17e-34: 124: 26.25
+	Hs
		1357712 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI35_HUMAN (18-229): 2.74e-32: 124: 12.67
+	Hs
		536760 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI27_HUMAN (22-228): 7.77e-33: 125: 15.49
+	Hs
		1377466 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRAF6_HUMAN (6-175): 2.58e-26: 108: 21.39
+	Hs
		551428 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RAG1_HUMAN (26-140): 1.98e-25: 106: 27.73
+	Hs
		1252560 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		LNX1_HUMAN (28-142): 7.17e-24: 101: 24.17
+	Mm
		895982 UB2D1_MOUSE (4-149): 3.22e-80: 235: 45.21		RNF41_MOUSE (37-120): 3.51e-10: 60.5: 24.18