HitPredict

Interactor 1: RAB14 (P61106)
Ras-related protein Rab-14 (EC 3.6.5.2)
Gene: RAB14

Interactor 2: VP13C (Q709C8)
Intermembrane lipid transfer protein VPS13C (Vacuolar protein sorting-associated protein 13C)
Gene: VPS13C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0005770 - late endosome GO:0005829 - cytosol GO:0006895 - Golgi to endosome transport and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 3753
+	Hs
		895141 RAB2A_HUMAN (8-195): 6.73e-96: 280: 62.77		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		591900 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		918895 RAB1A_HUMAN (1-215): 1.44e-87: 258: 42.33		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		914157 RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		1173713 RAB1B_HUMAN (4-215): 8.23e-84: 249: 40.57		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		1173694 RAB2B_HUMAN (8-215): 1.34e-81: 244: 55.14		VP13C_HUMAN (1-3753): 0: 4013: 100.00
+	Hs
		895235 RAB2A_HUMAN (8-195): 6.73e-96: 280: 62.77		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Hs
		591985 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Hs
		914296 RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54		VP13A_HUMAN (1-1615): 0: 1188: 38.34
+	Hs
		591971 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		ATG2B_HUMAN (4-362): 1.94e-59: 231: 16.75
+	Hs
		591865 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		ATG2A_HUMAN (4-362): 4.38e-52: 206: 14.71
+	Hs
		47676 RAB1A_HUMAN (1-215): 1.44e-87: 258: 42.33		A0AUL9_HUMAN (4-362): 8.15e-56: 206: 14.71
+	Hs
		591879 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		VP13D_HUMAN (1041-2048): 1.94e-43: 179: 14.23
+	Hs
		591908 RAB4A_HUMAN (8-215): 1.05e-87: 259: 60.77		VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22
+	Hs
		914175 RB11A_HUMAN (1-213): 8.5e-86: 254: 45.54		VP13B_HUMAN (2-275): 5.08e-38: 160: 21.22
+	Dm
		185550 RAB2_DROME (7-214): 5.76e-82: 244: 57.08		Q9VAD3_DROME (3-346): 6.09e-32: 140: 15.81