Protein: GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]

Gene: GEPH, GPHN
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q9NQX3

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

991723

DYL1
Dynein light chain 1, cytoplasmic

6

2

Small-scale

0.736

High

1390722

DYL2
Dynein light chain 2, cytoplasmic

4

2

High-throughput

0.691

High

1416657

TSSK1
Testis-specific serine/threonine-protein kinase 1

4

2

High-throughput

0.691

High

243027

PRKN
E3 ubiquitin-protein ligase parkin

3

1

High-throughput

0.640

High

1187334

CMA1D
Protein CIMAP1D

3

0

High-throughput

0.638

High

213376

ARHG9
Rho guanine nucleotide exchange factor 9

3

0

Small-scale

0.630

High

1447548

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

9

High-throughput

0.621

High

870834

GLRB
Glycine receptor subunit beta

2

7

Small-scale

0.619

High

183196

KMO
Kynurenine 3-monooxygenase

2

0

High-throughput

0.602

High

398010

KLKB1
Plasma kallikrein

2

0

High-throughput

0.602

High

459764

PROF1
Profilin-1

2

2

Small-scale

0.595

High

896642

VASP
Vasodilator-stimulated phosphoprotein

2

4

Small-scale

0.584

High

681045

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

67181

ZAR1L
Protein ZAR1-like

2

0

High-throughput

0.576

High

1400149

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

0

High-throughput

0.576

High

67713

RHG32
Rho GTPase-activating protein 32

2

2

High-throughput

0.571

High

839379

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.537

High

159401

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

1

High-throughput

0.536

High

476517

STS
Steryl-sulfatase

1

1

High-throughput

0.536

High

728439

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.536

High

966914

1433G
14-3-3 protein gamma

1

1

High-throughput

0.536

High

993343

ACTG
Actin, cytoplasmic 2

1

1

High-throughput

0.536

High

1204466

ARSH
Arylsulfatase H

1

1

High-throughput

0.536

High

462663

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.513

High

1032424

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.513

High

1390541

CDCA5
Sororin

1

0

High-throughput

0.513

High

1416880

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

1

0

High-throughput

0.513

High

269616

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

2

Small-scale

0.501

High

862482

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

995836

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

1324083

RHG24
Rho GTPase-activating protein 24

1

2

High-throughput

0.479

High

1331365

ENAH
Protein enabled homolog

1

4

Small-scale

0.479

High

1428373

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

1

High-throughput

0.479

High

1428981

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1433977

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1059975

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

High-throughput

0.460

High

341685

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.458

High

412661

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

414684

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

483400

CLCB
Clathrin light chain B

1

0

High-throughput

0.458

High

621761

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

772418

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

831485

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

901597

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

957524

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

971139

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

986751

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

996353

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.458

High

1067750

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1114387

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1255683

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1289646

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1332902

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.458

High

1433784

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.458

High

1435333

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1447549

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1447550

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

888566

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

1

High-throughput

0.439

High

404924

PRIO
Major prion protein

1

0

High-throughput

0.426

High

530421

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1129278

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.426

High

1398368

CEP63
Centrosomal protein of 63 kDa

1

0

High-throughput

0.426

High

1417615

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

0

High-throughput

0.426

High

209341

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

4

0

High-throughput

0.367

High

1063876

LG3BP
Galectin-3-binding protein

3

0

High-throughput

0.345

High

1357850

MITD1
MIT domain-containing protein 1

2

0

High-throughput

0.316

High

106700

APRIO
Alternative prion protein

2

0

High-throughput

0.305

High

1193237

SPAS1
Spermatogenesis-associated serine-rich protein 1

1

0

High-throughput

0.282

High

587231

ITF2
Transcription factor 4

1

0

High-throughput

0.279

Low

1198858

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.279

Low

1383689

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

848353

MAGA4
Melanoma-associated antigen 4

1

0

High-throughput

0.232

Low

1314433

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low

1428251

TGIF2
Homeobox protein TGIF2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025