HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	31722399
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 1493
+	Hs
		891769 ACTB_HUMAN (1-414): 0: 539: 35.66		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		891731 ACTB_HUMAN (1-414): 0: 539: 35.66		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		929837 ACTG_HUMAN (1-414): 0: 538: 35.42		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		932158 ACTC_HUMAN (3-414): 0: 527: 35.59		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		932125 ACTC_HUMAN (3-414): 0: 527: 35.59		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		846911 ARP3_HUMAN (1-418): 0: 588: 100.00		SMCA4_HUMAN (228-1324): 0: 677: 19.90
+	Hs
		846733 ARP3_HUMAN (1-418): 0: 588: 100.00		SMCA2_HUMAN (228-1247): 0: 660: 19.72
+	Hs
		229358 ACTC_HUMAN (3-414): 0: 527: 35.59		SMCA5_HUMAN (368-1383): 0: 698: 20.75
+	Hs
		846910 ACTB_HUMAN (1-414): 0: 539: 35.66		SMCA4_HUMAN (228-1324): 0: 677: 19.90
+	Hs
		846917 ACTG_HUMAN (1-414): 0: 538: 35.42		SMCA4_HUMAN (228-1324): 0: 677: 19.90
+	Zm
		13638 A0A1D6FW13_MAIZE (2-414): 0: 526: 35.02		A0A1D6MT91_MAIZE (363-1391): 0: 686: 20.61
+	Mm
		929785 ACTG_MOUSE (1-414): 0: 538: 35.42		SMCA4_MOUSE (228-1233): 0: 674: 19.35
+	Hs
		846919 ACTS_HUMAN (3-414): 0: 528: 35.59		SMCA4_HUMAN (228-1324): 0: 677: 19.90
+	Mm
		929795 ACTG_MOUSE (1-414): 0: 538: 35.42		SMCA2_MOUSE (54-1233): 0: 667: 18.48
+	Hs
		846918 ACTC_HUMAN (3-414): 0: 527: 35.59		SMCA4_HUMAN (228-1324): 0: 677: 19.90
+	Dm
		501486 ACT1_DROME (3-414): 0: 534: 35.35		BRM_DROME (228-1361): 0: 662: 18.59
+	Xl
		292752 ACTB_XENLA (1-414): 0: 538: 35.66		Q4VQ79_XENLA (233-1201): 0: 657: 20.11
+	Dm
		361138 ACT2_DROME (3-414): 0: 532: 35.11		BRM_DROME (228-1361): 0: 662: 18.59
+	Hs
		846742 ACTC_HUMAN (3-414): 0: 527: 35.59		SMCA2_HUMAN (228-1247): 0: 660: 19.72