HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0030027 - lamellipodium GO:0051015 - actin filament binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 474
+	Hs
		892108 ACTB_HUMAN (1-414): 0: 539: 35.66		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		930051 ACTG_HUMAN (1-414): 0: 538: 35.42		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932449 ACTC_HUMAN (3-414): 0: 527: 35.59		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		932355 ACTC_HUMAN (3-414): 0: 527: 35.59		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		884629 ARP3_HUMAN (1-418): 0: 588: 100.00		CORO7_HUMAN (2-203): 2.45e-23: 105: 12.22
+	Hs
		932318 ACTC_HUMAN (3-414): 0: 527: 35.59		SNR40_HUMAN (160-435): 1.36e-38: 145: 11.87
+	Hs
		932185 ACTC_HUMAN (3-414): 0: 527: 35.59		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		891943 ACTB_HUMAN (1-414): 0: 539: 35.66		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		929956 ACTG_HUMAN (1-414): 0: 538: 35.42		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Hs
		884627 ACTB_HUMAN (1-414): 0: 539: 35.66		CORO7_HUMAN (2-203): 2.45e-23: 105: 12.22
+	Sc
		887686 ACT_YEAST (1-414): 0: 528: 34.94		CORO_YEAST (2-228): 2.02e-24: 108: 12.16
+	Hs
		891660 ACTB_HUMAN (1-414): 0: 539: 35.66		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		903110 ACTG_HUMAN (1-414): 0: 538: 35.42		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Sc
		811965 ARP3_YEAST (6-417): 1.14e-171: 489: 58.35		CORO_YEAST (2-228): 2.02e-24: 108: 12.16