HitPredict

Interactor 1: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 394 Hs			1 1068
+	Hs
		724743 ARP2_HUMAN (1-394): 0: 815: 100.00		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		211550 ARP2_HUMAN (1-394): 0: 815: 100.00		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		896980 ARP2_HUMAN (1-394): 0: 815: 100.00		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Oc
		933099 ACTS_RABIT (2-388): 0: 569: 46.51		Q07931_RABIT (960-1066): 1.72e-45: 167: 39.82
+	Hs
		725135 ACTH_HUMAN (1-388): 0: 569: 45.62		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Mm
		892168 ACTB_MOUSE (1-388): 0: 574: 46.65		MILK2_MOUSE (962-1066): 3.4e-34: 144: 38.68
+	Hs
		891887 ACTB_HUMAN (1-388): 0: 574: 46.65		MILK2_HUMAN (962-1066): 5.25e-33: 140: 37.74
+	Hs
		724738 ACTB_HUMAN (1-388): 0: 574: 46.65		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		724762 ACTG_HUMAN (3-388): 0: 573: 46.37		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		724767 ACTS_HUMAN (2-388): 0: 569: 46.51		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Mm
		892205 ACTB_MOUSE (1-388): 0: 574: 46.65		MYH9_MOUSE (414-983): 4.64e-20: 99.2: 11.36
+	Rn
		892228 ACTB_RAT (1-388): 0: 574: 46.65		MYH9_RAT (416-983): 2.69e-18: 93.4: 9.48
+	Hs
		506816 ACTB_HUMAN (1-388): 0: 574: 46.65		SPTB1_HUMAN (963-1066): 1.78e-16: 87.4: 45.71
+	Rn
		892236 ACTB_RAT (1-388): 0: 574: 46.65		MYH10_RAT (450-986): 2.83e-15: 83.4: 10.09
+	Hs
		725637 ACTB_HUMAN (1-388): 0: 574: 46.65		ACTN2_HUMAN (963-1066): 3.61e-15: 82.4: 40.95
+	Hs
		211548 ACTB_HUMAN (1-388): 0: 574: 46.65		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		211560 ACTC_HUMAN (2-388): 0: 569: 46.51		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		211561 ACTS_HUMAN (2-388): 0: 569: 46.51		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		930015 ACTG_HUMAN (3-388): 0: 573: 46.37		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		929896 ACTG_HUMAN (3-388): 0: 573: 46.37		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36