HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 568
+	Hs
		299512 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH18_HUMAN (5-565): 1.58e-159: 469: 39.79
+	Hs
		897321 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLHL8_HUMAN (5-565): 5.61e-156: 461: 37.41
+	Hs
		1024168 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00
+	Hs
		1120807 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00
+	Hs
		299514 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH18_HUMAN (5-565): 1.58e-159: 469: 39.79
+	Hs
		1024231 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLHL8_HUMAN (5-565): 5.61e-156: 461: 37.41
+	Hs
		299532 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH18_HUMAN (5-565): 1.58e-159: 469: 39.79
+	Hs
		897322 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06
+	Hs
		897262 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH10_HUMAN (428-568): 1.65e-33: 136: 33.80
+	Hs
		897264 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH24_HUMAN (394-568): 1.15e-28: 122: 29.67
+	Hs
		1024234 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06
+	Hs
		1024232 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLHL9_HUMAN (380-568): 3.91e-43: 164: 27.55
+	Hs
		1311911 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06
+	Hs
		1024184 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH36_HUMAN (379-567): 1.6e-35: 143: 25.63
+	Hs
		1024172 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH10_HUMAN (428-568): 1.65e-33: 136: 33.80
+	Hs
		1024173 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH24_HUMAN (394-568): 1.15e-28: 122: 29.67
+	Hs
		1153792 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH10_HUMAN (428-568): 1.65e-33: 136: 33.80