HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	26186194, 28514442, 33961781, 12732143, 16260596, 19295130
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 427
+	Hs
		897238 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21
+	Hs
		1024195 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		DDB2_HUMAN (1-427): 1.81e-95: 294: 100.00
+	Hs
		87386 C9JFE4_HUMAN (17-443): 1.42e-78: 253: 14.93		DDB2_HUMAN (1-427): 1.81e-95: 294: 100.00
+	Hs
		1265891 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		DDB2_HUMAN (1-427): 1.81e-95: 294: 100.00
+	Hs
		121828 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		FBXW7_HUMAN (5-311): 1.3e-61: 213: 12.14
+	Hs
		121725 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		1024152 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21
+	Hs
		121982 PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		1028022 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21