HitPredict

Interactor 1: CSN2 (P61202)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: Cops2

Interactor 2: CSN7A (Q9CZ04)
COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (JAB1-containing signalosome subunit 7a)
Gene: Cops7a

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24973710
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PCI~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0008180 - COP9 signalosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Mm			1 275
+	Hs
		897324 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		CSN7A_HUMAN (1-275): 4.23e-101: 298: 98.91
+	Hs
		897312 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		CSN7B_HUMAN (1-267): 2.01e-87: 262: 57.30
+	Dm
		1277031 CSN2_DROME (16-443): 5.59e-115: 345: 83.92		CSN7_DROME (2-268): 1.73e-88: 266: 41.95
+	Mm
		102353 G3UXW9_MOUSE (17-443): 1.81e-80: 259: 15.39		CSN7A_MOUSE (1-275): 2.17e-100: 296: 100.00
+	Hs
		1024236 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		CSN7A_HUMAN (1-275): 4.23e-101: 298: 98.91
+	Hs
		1311913 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		CSN7A_HUMAN (1-275): 4.23e-101: 298: 98.91
+	At
		1278364 PSD11_ARATH (42-443): 2.17e-80: 256: 22.98		CSN7_ARATH (1-266): 2.65e-91: 272: 29.59
+	Mm
		102351 G3UXW9_MOUSE (17-443): 1.81e-80: 259: 15.39		CSN7B_MOUSE (1-267): 1.25e-88: 265: 58.05
+	Mm
		1207344 CSN1_MOUSE (17-443): 1.68e-79: 255: 15.39		CSN7B_MOUSE (1-267): 1.25e-88: 265: 58.05
+	Hs
		1024222 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		CSN7B_HUMAN (1-267): 2.01e-87: 262: 57.30
+	An
		961357 CSN2_EMENI (1-440): 6.53e-108: 330: 50.67		CSN7_EMENI (1-229): 1.87e-53: 178: 28.87
+	Hs
		1311900 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		CSN7B_HUMAN (1-267): 2.01e-87: 262: 57.30
+	Ce
		136315 CSN2_CAEEL (17-417): 3.31e-102: 315: 65.93		EIF3M_CAEEL (1-198): 1.15e-48: 167: 17.96
+	Hs
		121872 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		PSD13_HUMAN (17-197): 9.5e-61: 198: 20.42
+	Hs
		1062898 PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01		PSD13_HUMAN (17-197): 9.5e-61: 198: 20.42
+	Hs
		122105 PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80		PSD13_HUMAN (17-197): 9.5e-61: 198: 20.42
+	Dm
		1180705 PSD11_DROME (36-442): 4.15e-87: 273: 20.34		Q7KMP8_DROME (24-197): 2.67e-55: 184: 20.11
+	Hs
		122044 PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80		EIF3M_HUMAN (2-188): 3.91e-58: 191: 21.65
+	Dm
		1180993 PSMD6_DROME (58-439): 1.55e-80: 255: 12.89		Q7KMP8_DROME (24-197): 2.67e-55: 184: 20.11
+	Sc
		978512 RPN6_YEAST (67-443): 8.69e-76: 245: 21.43		RPN9_YEAST (12-195): 4.97e-50: 171: 19.59