HitPredict

Interactor 1: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019003 - GDP binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 196
+	Hs
		897878 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		918847 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		897874 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545300 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		900355 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915582 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545307 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436236 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		436244 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		918849 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892300 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		893855 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		892305 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		893872 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		436498 RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		894409 RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564467 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		564470 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120375 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		120378 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98