HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (EC 3.6.1.-) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.802

Property	Details
Experiments	35271311, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Tubulin, Cpn60_TCP1~Tubulin_C
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0005929 - cilium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 451
+	Hs
		899204 TCPQ_HUMAN (1-548): 0: 616: 100.00		TBA1C_HUMAN (1-451): 0: 725: 98.00
+	Hs
		898992 TCPQ_HUMAN (1-548): 0: 616: 100.00		TBA4A_HUMAN (1-450): 0: 716: 96.44
+	Hs
		899104 TCPQ_HUMAN (1-548): 0: 616: 100.00		TBA1A_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457313 TCPQ_HUMAN (1-548): 0: 616: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		898993 TCPQ_HUMAN (1-548): 0: 616: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		1407535 TCPH_HUMAN (9-538): 0: 564: 26.39		TBA1C_HUMAN (1-451): 0: 725: 98.00
+	Mm
		997239 TCPH_MOUSE (9-546): 0: 573: 26.92		TBA1A_MOUSE (1-440): 0: 712: 99.55
+	Hs
		882121 TCPG_HUMAN (10-547): 0: 558: 28.21		TBA1C_HUMAN (1-451): 0: 725: 98.00
+	Hs
		997096 TCPH_HUMAN (9-538): 0: 564: 26.39		TBA4A_HUMAN (1-450): 0: 716: 96.44
+	Hs
		996823 TCPH_HUMAN (9-538): 0: 564: 26.39		TBA1B_HUMAN (1-440): 0: 714: 100.00
+	Hs
		1259452 TCPH_HUMAN (9-538): 0: 564: 26.39		TBA1A_HUMAN (1-440): 0: 712: 99.55
+	Hs
		881873 TCPG_HUMAN (10-547): 0: 558: 28.21		TBA4A_HUMAN (1-450): 0: 716: 96.44
+	Hs
		881872 TCPG_HUMAN (10-547): 0: 558: 28.21		TBA1B_HUMAN (1-440): 0: 714: 100.00
+	Hs
		881999 TCPG_HUMAN (10-547): 0: 558: 28.21		TBA1A_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457645 TCPH_HUMAN (9-538): 0: 564: 26.39		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		1244138 TCPH_HUMAN (9-538): 0: 564: 26.39		TBA3E_HUMAN (1-440): 0: 697: 96.59
+	Hs
		997479 TCPH_HUMAN (9-538): 0: 564: 26.39		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		881874 TCPG_HUMAN (10-547): 0: 558: 28.21		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		881988 TCPG_HUMAN (10-547): 0: 558: 28.21		TBA3E_HUMAN (1-440): 0: 697: 96.59
+	Mm
		997240 TCPD_MOUSE (2-525): 0: 536: 27.90		TBA1A_MOUSE (1-440): 0: 712: 99.55