HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (EC 3.6.1.-) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Cpn60_TCP1
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 539 Hs			1 418
+	Hs
		899614 TCPD_HUMAN (1-539): 0: 601: 100.00		ARP3B_HUMAN (1-418): 0: 580: 90.67
+	Hs
		881855 TCPG_HUMAN (12-537): 0: 552: 33.40		ARP3_HUMAN (1-418): 0: 588: 100.00
+	Hs
		899318 TCPD_HUMAN (1-539): 0: 601: 100.00		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		899336 TCPD_HUMAN (1-539): 0: 601: 100.00		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		958178 TCPH_HUMAN (12-538): 0: 548: 32.34		ARP3_HUMAN (1-418): 0: 588: 100.00
+	Hs
		882200 TCPG_HUMAN (12-537): 0: 552: 33.40		ARP3B_HUMAN (1-418): 0: 580: 90.67
+	Hs
		899339 TCPD_HUMAN (1-539): 0: 601: 100.00		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Hs
		1407604 TCPH_HUMAN (12-538): 0: 548: 32.34		ARP3B_HUMAN (1-418): 0: 580: 90.67
+	Hs
		899338 TCPD_HUMAN (1-539): 0: 601: 100.00		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Hs
		875892 TCPE_HUMAN (13-535): 0: 539: 37.88		ARP3_HUMAN (1-418): 0: 588: 100.00
+	Hs
		899329 TCPD_HUMAN (1-539): 0: 601: 100.00		ACTA_HUMAN (3-414): 0: 526: 35.59
+	Sc
		811010 TCPD_YEAST (22-539): 0: 570: 59.20		ACT_YEAST (1-414): 0: 528: 34.94
+	Hs
		881853 TCPG_HUMAN (12-537): 0: 552: 33.40		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		881869 TCPG_HUMAN (12-537): 0: 552: 33.40		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		953055 TCPH_HUMAN (12-538): 0: 548: 32.34		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		993309 TCPH_HUMAN (12-538): 0: 548: 32.34		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		881871 TCPG_HUMAN (12-537): 0: 552: 33.40		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Hs
		875890 TCPE_HUMAN (13-535): 0: 539: 37.88		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		995790 TCPH_HUMAN (12-538): 0: 548: 32.34		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Sc
		810978 TCPD_YEAST (22-539): 0: 570: 59.20		ARP3_YEAST (6-417): 1.14e-171: 489: 58.35