Interactor 1: WNT3A (P56704)
Protein Wnt-3a
Gene: WNT3A

Interactor 2: FZD2 (Q14332)
Frizzled-2 (Fz-2) (hFz2) (FzE2)
Gene: FZD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 19910923, 29748286
Identification Methods affinity chromatography technology, bio-layer interferometry
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Fz~wnt
Common GO terms GO:0005886 - plasma membrane
GO:0030182 - neuron differentiation
GO:0035567 - non-canonical Wnt signaling pathway
GO:0045893 - positive regulation of DNA-templated transcription
GO:0060070 - canonical Wnt signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 352
Hs

1 565
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024