HitPredict

Interactor 1: ISL1 (P61372)
Insulin gene enhancer protein ISL-1 (Islet-1)
Gene: ISL1

Interactor 2: SSBP3 (Q9D032)
Single-stranded DNA-binding protein 3 (Lck-associated signal transducer) (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26495868
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0008284 - positive regulation of cell population proliferation GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 349 Mm			1 388
+	Hs
		899933 ISL1_HUMAN (1-349): 1.96e-89: 274: 100.00		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		1283496 ISL2_HUMAN (1-349): 3.08e-80: 250: 73.35		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Mm
		1321868 ISL2_MOUSE (1-349): 4.08e-80: 250: 72.21		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		899932 ISL1_HUMAN (1-349): 1.96e-89: 274: 100.00		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		1283495 ISL2_HUMAN (1-349): 3.08e-80: 250: 73.35		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Mm
		899943 ISL1_MOUSE (1-349): 1.96e-89: 274: 100.00		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		899917 ISL1_HUMAN (1-349): 1.96e-89: 274: 100.00		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Mm
		1112383 ISL2_MOUSE (1-349): 4.08e-80: 250: 72.21		Q3U4B1_MOUSE (1-388): 1.81e-48: 169: 62.66
+	Mm
		1321929 LHX2_MOUSE (3-316): 2.14e-59: 198: 25.82		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		839819 LHX2_HUMAN (3-316): 1.86e-58: 195: 25.55		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		1314903 LHX9_HUMAN (3-304): 5.38e-58: 194: 26.27		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Mm
		1321867 ISL2_MOUSE (1-349): 4.08e-80: 250: 72.21		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		946656 ISL2_HUMAN (1-349): 3.08e-80: 250: 73.35		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		839818 LHX2_HUMAN (3-316): 1.86e-58: 195: 25.55		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		1314654 LHX9_HUMAN (3-304): 5.38e-58: 194: 26.27		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		822672 LHX1_HUMAN (16-349): 3.6e-57: 192: 27.35		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Mm
		1321891 LHX2_MOUSE (3-316): 2.14e-59: 198: 25.82		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		839725 LHX2_HUMAN (3-316): 1.86e-58: 195: 25.55		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		822624 LHX1_HUMAN (16-349): 3.6e-57: 192: 27.35		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		839836 LHX2_HUMAN (3-316): 1.86e-58: 195: 25.55		CHD7_HUMAN (99-332): 1.72e-32: 131: 17.60