Interactor 1: VA0D1 (P61421)
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)
Gene: ATP6V0D1

Interactor 2: VAS1 (Q15904)
V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1)
Gene: ATP6AP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ac45-VOA1_TM~vATP-synt_AC39
Common GO terms GO:0005765 - lysosomal membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016020 - membrane
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 351
Hs

1 470
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024