HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PAR3L (Q8TEW8)
Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein)
Gene: PARD3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005938 - cell cortex GO:0030054 - cell junction GO:0043296 - apical junction complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1205
+	Hs
		436426 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PAR3L_HUMAN (1-1205): 0: 674: 100.00
+	Hs
		900726 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Hs
		925463 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Hs
		436425 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PARD3_HUMAN (1-1181): 5.16e-119: 403: 34.95
+	Hs
		900762 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG3_HUMAN (25-525): 3.4e-49: 191: 14.95
+	Mm
		925797 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		DLG4_MOUSE (334-877): 1.2e-48: 187: 16.58
+	Hs
		900424 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Hs
		925239 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Hs
		436278 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		DLG1_HUMAN (47-699): 1.29e-44: 177: 11.61
+	Hs
		900463 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SCRIB_HUMAN (363-1198): 3.45e-31: 135: 12.27
+	Hs
		925273 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SCRIB_HUMAN (363-1198): 3.45e-31: 135: 12.27
+	Hs
		436297 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		SCRIB_HUMAN (363-1198): 3.45e-31: 135: 12.27
+	Hs
		436419 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		LNX1_HUMAN (289-749): 3.58e-27: 121: 15.17
+	Hs
		900710 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		INADL_HUMAN (162-321): 1.92e-13: 77.8: 14.91
+	Hs
		900421 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PTN13_HUMAN (138-337): 1.02e-12: 75.4: 14.71
+	Hs
		925236 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PTN13_HUMAN (138-337): 1.02e-12: 75.4: 14.71
+	Hs
		900820 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MAGI1_HUMAN (333-687): 4.75e-12: 73.1: 13.58
+	Hs
		925536 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MAGI1_HUMAN (333-687): 4.75e-12: 73.1: 13.58
+	Dm
		776889 RAC1_DROME (1-193): 2.11e-77: 231: 54.12		SCRIB_DROME (504-689): 1.03e-13: 78.5: 18.52
+	Hs
		436277 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		PTN13_HUMAN (138-337): 1.02e-12: 75.4: 14.71