Interactor 1: EREG (O14944)
Proepiregulin [Cleaved into: Epiregulin (EPR)]
Gene: EREG
Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.73 | 0.60 | 0.662 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0007173 - epidermal growth factor receptor signaling pathway GO:0008284 - positive regulation of cell population proliferation GO:0030297 - transmembrane receptor protein tyrosine kinase activator activity and 6 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
