HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: FRS2 (Q8WU20)
Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1)
Gene: FRS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 508
+	Hs
		925468 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		436429 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		951184 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		894251 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		545522 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		892505 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		915865 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		297820 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297823 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297809 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297827 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297812 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297819 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297822 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		120250 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29