HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: HDAC7 (Q8WUI4)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 952
+	Hs
		925469 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		HDAC7_HUMAN (1-952): 0: 1051: 100.00
+	Hs
		894252 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		HDAC7_HUMAN (1-952): 0: 1051: 100.00
+	Hs
		545523 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		HDAC7_HUMAN (1-952): 0: 1051: 100.00
+	Hs
		892506 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		HDAC7_HUMAN (1-952): 0: 1051: 100.00
+	Mm
		925822 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		Q9JM08_MOUSE (518-951): 5.78e-159: 475: 20.00
+	Hs
		545545 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		HDA10_HUMAN (520-943): 1.36e-152: 467: 36.39
+	Hs
		925697 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		HDAC6_HUMAN (443-951): 2.96e-115: 383: 30.33
+	Hs
		894550 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		HDAC6_HUMAN (443-951): 2.96e-115: 383: 30.33