Protein: AL1A3
Retinaldehyde dehydrogenase 3 (RALDH-3) (RalDH3) (EC 1.2.1.36) (Aldehyde dehydrogenase 6) (Aldehyde dehydrogenase family 1 member A3) (ALDH1A3)

Gene: AL1A3, ALDH1A3
Organism: Homo sapiens
Interactions: 57
UniProt ID: P47895

Gene Ontology (top 5):
GO:0001758 - retinal dehydrogenase (NAD+) activity
GO:0002072 - optic cup morphogenesis involved in camera-type eye development
GO:0002138 - retinoic acid biosynthetic process
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0004030 - aldehyde dehydrogenase [NAD(P)+] activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

400462

RAF1
RAF proto-oncogene serine/threonine-protein kinase

3

2

High-throughput

0.633

High

868090

MYOME
Myomegalin

2

1

High-throughput

0.611

High

868100

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

868107

SMOX
Spermine oxidase

2

0

High-throughput

0.602

High

868096

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

5

Small-scale

0.578

High

584492

VAV
Proto-oncogene vav

2

2

High-throughput

0.571

High

631112

RAB5A
Ras-related protein Rab-5A

2

1

High-throughput

0.571

High

868084

GRB10
Growth factor receptor-bound protein 10

2

1

High-throughput

0.571

High

868088

KPCD1
Serine/threonine-protein kinase D1

2

1

High-throughput

0.571

High

868098

SH3K1
SH3 domain-containing kinase-binding protein 1

2

2

High-throughput

0.571

High

868086

ITA9
Integrin alpha-9

2

1

High-throughput

0.558

High

868094

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

254878

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.536

High

602759

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

868079

CYC
Cytochrome c

1

1

High-throughput

0.536

High

868080

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.536

High

868105

TARA
TRIO and F-actin-binding protein

1

1

High-throughput

0.536

High

868082

CAV1
Caveolin-1

2

2

High-throughput

0.521

High

629491

PO3F3
POU domain, class 3, transcription factor 3

1

0

High-throughput

0.513

High

868076

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

868078

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.513

High

868081

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

High-throughput

0.513

High

868097

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

868103

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

868110

CHMP3
Charged multivesicular body protein 3

1

0

High-throughput

0.513

High

325300

OR2A4
Olfactory receptor 2A4

1

3

High-throughput

0.489

High

868071

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

868077

DSCR6
Protein ripply3

1

1

High-throughput

0.489

High

868083

GABPA
GA-binding protein alpha chain

1

1

High-throughput

0.489

High

868108

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

1

High-throughput

0.489

High

868113

RPKL1
Ribosomal protein S6 kinase-like 1

1

2

High-throughput

0.489

High

868075

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.479

High

868089

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

High-throughput

0.479

High

284087

SRS10
Serine/arginine-rich splicing factor 10

1

0

Small-scale

0.458

High

868073

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

868074

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

868085

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

868087

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

0

High-throughput

0.458

High

538736

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

5

High-throughput

0.445

High

868111

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.437

High

868101

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.426

High

868106

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.426

High

96893

E9PDS3
Integrin subunit alpha 9

1

1

High-throughput

0.407

High

261120

NSMA
Sphingomyelin phosphodiesterase 2

1

2

High-throughput

0.407

High

868109

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

1

High-throughput

0.407

High

868102

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

868093

CFA46
Cilia- and flagella-associated protein 46

2

0

High-throughput

0.313

High

226937

LIAS
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.279

Low

868072

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

868091

PATE2
Prostate and testis expressed protein 2

1

0

High-throughput

0.279

Low

868092

HACD2
Very-long-chain

1

0

High-throughput

0.279

Low

868095

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

868099

ZHX1R
Zinc fingers and homeoboxes protein 1, isoform 2

1

0

High-throughput

0.279

Low

418001

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

868112

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

0

Small-scale

0.238

Low

511031

PNM6A
Paraneoplastic antigen-like protein 6A

1

0

High-throughput

0.232

Low

868104

TX101
Testis-expressed protein 101

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025