HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 529
+	Hs
		147862 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG33_HUMAN (173-520): 5.6e-71: 248: 16.02
+	Hs
		64681 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54
+	Mm
		925803 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG32_MOUSE (173-497): 1.14e-61: 221: 14.54
+	Hs
		64688 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54
+	Hs
		200213 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SRGP3_HUMAN (66-474): 1.81e-60: 217: 11.16
+	Hs
		925192 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG04_HUMAN (50-412): 8.1e-61: 217: 12.40
+	Mm
		925802 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CHIO_MOUSE (169-393): 5.7e-65: 216: 12.72
+	Hs
		900637 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SRGP1_HUMAN (66-474): 6.27e-59: 213: 12.77
+	Mm
		1265268 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		SRGP1_MOUSE (55-474): 4e-57: 207: 12.30
+	Hs
		856140 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CHIO_HUMAN (169-393): 3.1e-61: 210: 12.72
+	Hs
		551044 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CHIN_HUMAN (169-393): 9.36e-61: 208: 14.47
+	Hs
		900817 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG07_HUMAN (123-438): 1.07e-56: 206: 12.39
+	Hs
		49631 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG10_HUMAN (66-528): 1.13e-56: 204: 13.10
+	Hs
		900747 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		STAR8_HUMAN (195-411): 8.38e-56: 203: 20.17
+	Hs
		900997 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GMIP_HUMAN (194-503): 7.56e-54: 197: 13.02
+	Hs
		900483 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG19_HUMAN (189-493): 5.18e-55: 194: 18.10
+	Hs
		900529 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG31_HUMAN (243-402): 4.62e-35: 142: 20.71
+	Sp
		195119 RHO1_SCHPO (1-193): 2.83e-94: 274: 66.83		RGA1_SCHPO (229-508): 8.03e-19: 92.5: 14.63
+	Hs
		900634 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG22_HUMAN (255-396): 3.52e-19: 92.9: 15.75
+	Mm
		925805 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG22_MOUSE (255-420): 6.69e-19: 92.2: 16.38