HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: MIA2 (Q96PC5)
Melanoma inhibitory activity protein 2 (MIA protein 2) (CTAGE family member 5 ER export factor) (Cutaneous T-cell lymphoma-associated antigen 5) (Meningioma-expressed antigen 6/11)
Gene: MIA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1412
+	Hs
		725138 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYH10_HUMAN (301-1315): 2.17e-50: 198: 10.21
+	Mm
		823539 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		CTRO_MOUSE (310-1114): 2.7e-31: 136: 12.74
+	Rn
		92842 RHOA_RAT (1-193): 4.1e-81: 240: 99.48		CTRO_RAT (310-1114): 8.59e-31: 134: 13.09
+	Mm
		823530 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CTRO_MOUSE (310-1114): 2.7e-31: 136: 12.74
+	Mm
		823529 CDC42_MOUSE (1-193): 5.51e-77: 230: 52.33		CTRO_MOUSE (310-1114): 2.7e-31: 136: 12.74
+	Hs
		900999 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		DAPLE_HUMAN (406-1129): 2.25e-28: 126: 11.65
+	Hs
		901094 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MRCKB_HUMAN (800-1144): 2.17e-20: 100: 14.17
+	Hs
		925766 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MRCKB_HUMAN (800-1144): 2.17e-20: 100: 14.17
+	Hs
		951494 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MRCKB_HUMAN (800-1144): 2.17e-20: 100: 14.17
+	Hs
		148608 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		CTRO_HUMAN (714-1069): 3.68e-14: 80.3: 18.54
+	Hs
		148653 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CTRO_HUMAN (714-1069): 3.68e-14: 80.3: 18.54
+	Hs
		900646 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		148297 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		CTRO_HUMAN (714-1069): 3.68e-14: 80.3: 18.54
+	Hs
		900553 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		TGO1_HUMAN (805-1411): 2.46e-12: 74.1: 12.91
+	Hs
		925402 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		436382 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		951304 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		UACA_HUMAN (710-1128): 4.96e-13: 76.5: 14.05
+	Hs
		724757 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MYH9_HUMAN (882-1300): 5.16e-11: 69.9: 11.91
+	Hs
		951124 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		724776 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYH9_HUMAN (882-1300): 5.16e-11: 69.9: 11.91