HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: SHLB2 (Q9NR46)
Endophilin-B2 (SH3 domain-containing GRB2-like protein B2)
Gene: SH3GLB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	16849557, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 395
+	Hs
		894478 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		SHLB2_HUMAN (1-395): 8.6e-89: 275: 100.00
+	Hs
		925314 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG44_HUMAN (12-361): 4.87e-47: 173: 18.23
+	Hs
		894068 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		RHG44_HUMAN (12-361): 4.87e-47: 173: 18.23
+	Hs
		901050 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PACN2_HUMAN (1-394): 2.63e-45: 164: 14.29
+	Hs
		925732 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PACN2_HUMAN (1-394): 2.63e-45: 164: 14.29
+	Hs
		951457 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		PACN2_HUMAN (1-394): 2.63e-45: 164: 14.29
+	Hs
		894589 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PACN2_HUMAN (1-394): 2.63e-45: 164: 14.29
+	Hs
		900425 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO1E_HUMAN (8-394): 2.62e-40: 154: 12.05
+	Hs
		925755 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		3BP1_HUMAN (15-353): 9.13e-41: 155: 15.39
+	Hs
		925240 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MYO1E_HUMAN (8-394): 2.62e-40: 154: 12.05
+	Hs
		436279 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		MYO1E_HUMAN (8-394): 2.62e-40: 154: 12.05
+	Hs
		580968 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		PLCG1_HUMAN (22-394): 6.24e-38: 147: 11.55
+	Hs
		925354 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG17_HUMAN (12-361): 1.74e-38: 149: 16.52
+	Hs
		950955 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MYO1E_HUMAN (8-394): 2.62e-40: 154: 12.05
+	Hs
		580973 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		PLCG1_HUMAN (22-394): 6.24e-38: 147: 11.55
+	Hs
		893949 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		MYO1E_HUMAN (8-394): 2.62e-40: 154: 12.05
+	Hs
		894126 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		RHG17_HUMAN (12-361): 1.74e-38: 149: 16.52
+	Hs
		925396 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SH3R1_HUMAN (296-394): 6.2e-15: 78.8: 18.18
+	Hs
		894097 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		SH319_HUMAN (338-394): 5.27e-13: 72.6: 38.60
+	Hs
		894047 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ITSN1_HUMAN (295-395): 2.46e-10: 64.7: 21.78