HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RHG20 (Q9P2F6)
Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)
Gene: ARHGAP20

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32203420
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RA~Ras, Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1191
+	Hs
		64681 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG32_HUMAN (318-1066): 3e-105: 368: 16.23
+	Hs
		900564 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG21_HUMAN (173-974): 1.04e-100: 354: 12.55
+	Hs
		900637 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		SRGP1_HUMAN (185-961): 3.78e-98: 339: 14.48
+	Mm
		1265268 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		SRGP1_MOUSE (185-961): 4.36e-91: 318: 13.89
+	Hs
		49631 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG10_HUMAN (177-705): 3.9e-87: 301: 14.50
+	Hs
		245183 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		OPHN1_HUMAN (171-785): 1.71e-86: 300: 12.44
+	Hs
		900540 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG29_HUMAN (151-924): 3.01e-83: 299: 15.87
+	Hs
		70663 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9A_HUMAN (116-809): 2.58e-79: 289: 15.71
+	Hs
		901048 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG26_HUMAN (171-635): 4.69e-80: 282: 12.12
+	Hs
		900634 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG22_HUMAN (230-870): 1.78e-80: 280: 14.65
+	Hs
		900997 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GMIP_HUMAN (234-719): 1.01e-77: 278: 17.92
+	Hs
		900529 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG31_HUMAN (351-1002): 1.46e-74: 274: 15.14
+	Hs
		900954 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG35_HUMAN (219-568): 7.74e-72: 265: 16.44
+	Hs
		901000 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG23_HUMAN (274-798): 4.6e-71: 263: 15.40
+	Hs
		900429 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG05_HUMAN (271-570): 1.2e-66: 249: 17.11
+	Hs
		900412 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG01_HUMAN (361-554): 4.07e-62: 220: 29.65
+	Hs
		900443 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9B_HUMAN (359-558): 2e-57: 220: 24.26
+	Mm
		1125742 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RHG01_MOUSE (361-552): 3.68e-61: 218: 29.95
+	Mm
		925791 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG01_MOUSE (361-552): 3.68e-61: 218: 29.95
+	Hs
		900532 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHGBB_HUMAN (360-518): 1.83e-12: 70.9: 33.54