Protein: S29A1
Equilibrative nucleoside transporter 1 (hENT1) (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (es nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1)

Gene: S29A1, SLC29A1
Organism: Homo sapiens
Interactions: 130
UniProt ID: Q99808

Gene Ontology (top 5):
GO:0001504 - neurotransmitter uptake
GO:0005326 - neurotransmitter transmembrane transporter activity
GO:0005337 - nucleoside transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006139 - nucleobase-containing compound metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375879

RASK
GTPase KRas

3

7

High-throughput

0.640

High

1330737

SIGL1
SIGLEC family-like protein 1

3

0

High-throughput

0.634

High

988651

RAC1
Ras-related C3 botulinum toxin substrate 1

3

8

High-throughput

0.633

High

132648

UPK1A
Uroplakin-1a

2

2

High-throughput

0.628

High

669057

FPR2
N-formyl peptide receptor 2

2

4

High-throughput

0.628

High

771218

APJ
Apelin receptor

2

2

High-throughput

0.628

High

845534

PI2R
Prostacyclin receptor

2

1

High-throughput

0.628

High

878082

AGRE5
Adhesion G protein-coupled receptor E5

2

2

High-throughput

0.628

High

926832

VMAT1
Chromaffin granule amine transporter

2

4

High-throughput

0.628

High

1291763

S22AG
Solute carrier family 22 member 16

2

3

High-throughput

0.628

High

1308951

S22A9
Organic anion transporter 7

2

3

High-throughput

0.628

High

1316358

AGRG5
Adhesion G-protein coupled receptor G5

2

2

High-throughput

0.628

High

1406354

GPR21
Probable G-protein coupled receptor 21

2

1

High-throughput

0.628

High

557445

SRC
Proto-oncogene tyrosine-protein kinase Src

2

1

High-throughput

0.621

High

142152

NPT3
Sodium-dependent phosphate transport protein 3

2

0

High-throughput

0.602

High

466954

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.602

High

855379

5HT3A
5-hydroxytryptamine receptor 3A

2

0

High-throughput

0.602

High

1197870

S39AC
Zinc transporter ZIP12

2

0

High-throughput

0.602

High

609787

LEG3
Galectin-3

2

1

High-throughput

0.601

High

125587

LEG9
Galectin-9

3

1

High-throughput

0.599

High

230408

CREB3
Cyclic AMP-responsive element-binding protein 3

2

2

High-throughput

0.590

High

374878

RASH
GTPase HRas

2

5

High-throughput

0.584

High

540642

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

978249

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

320491

TM63A
Mechanosensitive cation channel TMEM63A

2

0

High-throughput

0.576

High

631435

RAB5A
Ras-related protein Rab-5A

2

2

High-throughput

0.571

High

218683

TGON2
Trans-Golgi network integral membrane protein 2

2

0

High-throughput

0.559

High

193614

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

0

High-throughput

0.547

High

164959

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

2

High-throughput

0.536

High

183959

S22A2
Solute carrier family 22 member 2

1

3

High-throughput

0.536

High

248500

O10H2
Olfactory receptor 10H2

1

1

High-throughput

0.536

High

351952

S1PR4
Sphingosine 1-phosphate receptor 4

1

3

High-throughput

0.536

High

833858

P2RY2
P2Y purinoceptor 2

1

3

High-throughput

0.536

High

867669

GPR12
G-protein coupled receptor 12

1

2

High-throughput

0.536

High

870773

CXA8
Gap junction alpha-8 protein

1

3

High-throughput

0.536

High

907051

CCR6
C-C chemokine receptor type 6

1

2

High-throughput

0.536

High

944369

NAC3
Sodium/calcium exchanger 3

1

1

High-throughput

0.536

High

1053055

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.536

High

1101642

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

3

High-throughput

0.536

High

1407390

NMUR2
Neuromedin-U receptor 2

1

1

High-throughput

0.536

High

1407397

NCKX3
Sodium/potassium/calcium exchanger 3

1

1

High-throughput

0.536

High

1407404

O10H1
Olfactory receptor 10H1

1

1

High-throughput

0.536

High

1327785

SH2D3
SH2 domain-containing protein 3C

2

2

High-throughput

0.521

High

702834

5HT2C
5-hydroxytryptamine receptor 2C

1

0

High-throughput

0.518

High

274721

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

407209

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

771810

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.513

High

984250

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.513

High

1007893

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1214366

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

1239038

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.513

High

1328490

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.513

High

1333592

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

1393193

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

1407389

TM2D2
TM2 domain-containing protein 2

1

0

High-throughput

0.513

High

1407391

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1407396

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.513

High

126766

RHOD
Rho-related GTP-binding protein RhoD

1

11

High-throughput

0.479

High

189799

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

341134

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.479

High

374160

RASN
GTPase NRas

1

7

High-throughput

0.479

High

463730

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

466432

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

562350

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

581256

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.479

High

601421

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.479

High

630616

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.479

High

710447

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.479

High

901006

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.479

High

901524

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

902030

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

953637

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

955519

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.479

High

962420

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

975201

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

1015715

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.479

High

1087259

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1145079

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1322964

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

1381499

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.479

High

1407393

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.479

High

1407394

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.479

High

1407401

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

226183

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

327424

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

414493

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

417706

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

580682

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

582934

EZRI
Ezrin

1

0

High-throughput

0.458

High

715738

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

1041246

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1163408

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1233445

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1334824

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1407400

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

640997

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

3

High-throughput

0.445

High

852836

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

3

High-throughput

0.445

High

1110704

DCTN2
Dynactin subunit 2

1

1

High-throughput

0.445

High

1366199

LPAR1
Lysophosphatidic acid receptor 1

1

3

High-throughput

0.445

High

1407402

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

3

High-throughput

0.445

High

956460

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.437

High

333156

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.426

High

827905

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.426

High

945848

EPIPL
Epiplakin

1

0

High-throughput

0.426

High

1407388

COR1B
Coronin-1B

1

0

High-throughput

0.426

High

1407395

POPD2
Popeye domain-containing protein 2

1

0

High-throughput

0.426

High

1407398

AT131
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.426

High

1407399

TM9S3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.426

High

1407403

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.426

High

49815

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

1326686

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1396504

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

1407405

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

891945

WHR1
Winged helix repair factor 1

1

0

Small-scale

0.265

Low

181729

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

457644

TBB5
Tubulin beta chain

1

0

High-throughput

0.249

Low

976515

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

1005022

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1141890

EEA1
Early endosome antigen 1

1

0

High-throughput

0.249

Low

1197687

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1255237

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1293125

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1370326

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

1381946

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

169136

ML12B
Myosin regulatory light chain 12B

1

0

High-throughput

0.232

Low

895955

F10A1
Hsc70-interacting protein

1

0

High-throughput

0.232

Low

915172

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.232

Low

1104068

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1211870

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

0

High-throughput

0.232

Low

1407392

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025