HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RIPR2 (Q9Y4F9)
Rho family-interacting cell polarization regulator 2
Gene: RIPOR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.719

Property	Details
Experiments	25416956, 21516116, 32296183, 21988832, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:1990869 - cellular response to chemokine
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 1068
+	Hs
		436588 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RIPR2_HUMAN (1-1068): 0: 1645: 100.00
+	Hs
		900807 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RIPR3_HUMAN (478-1049): 0: 570: 29.03
+	Hs
		436462 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RIPR3_HUMAN (478-1049): 0: 570: 29.03
+	Hs
		900611 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RIPR1_HUMAN (16-579): 1.41e-169: 532: 40.72