HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0019901 - protein kinase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 447
+	Hs
		436191 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		LIS1_HUMAN (3-218): 5.36e-51: 179: 11.86
+	Mm
		892718 CDC42_MOUSE (1-193): 5.51e-77: 230: 52.33		LIS1_MOUSE (3-218): 3.88e-51: 179: 11.86
+	Hs
		900348 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		436239 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		900362 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Hs
		545720 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		TBL2_HUMAN (308-446): 2.02e-13: 73.6: 12.10