HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 244 Hs			1 377
+	Hs
		436249 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		915593 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		915594 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		ACTS_HUMAN (1-377): 0: 598: 97.88
+	Hs
		891672 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		925178 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		545292 RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		900364 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		ACTC_HUMAN (1-377): 0: 598: 98.41
+	Hs
		900353 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		ACTA_HUMAN (1-377): 0: 596: 100.00
+	Hs
		915362 RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47		ACTA_HUMAN (1-377): 0: 596: 100.00
+	Hs
		892042 RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		915511 RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21		ACTA_HUMAN (1-377): 0: 596: 100.00