HitPredict

Interactor 1: S61A1 (P61619)
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)
Gene: SEC61A1

Interactor 2: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 890
+	Rn
		544803 S61A1_RAT (1-476): 0: 717: 100.00		INSR_RAT (232-788): 7.04e-127: 416: 27.65
+	Hs
		441474 S61A1_HUMAN (1-476): 0: 717: 100.00		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		435593 S61A1_HUMAN (1-476): 0: 717: 100.00		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		411348 S61A1_HUMAN (1-476): 0: 717: 100.00		INSR_HUMAN (292-790): 2.17e-60: 226: 31.15
+	Hs
		445840 S61A1_HUMAN (1-476): 0: 717: 100.00		ROS1_HUMAN (279-787): 2.73e-55: 211: 30.76
+	Hs
		609236 S61A1_HUMAN (1-476): 0: 717: 100.00		FGFR3_HUMAN (7-315): 1.59e-17: 89.8: 14.60
+	Hs
		674378 S61A1_HUMAN (1-476): 0: 717: 100.00		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56